Emmanouel Anna, Mouza Eirini, Kessels Roy P C, Fasotti Luciano
Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen , The Netherlands .
Brain Inj. 2014;28(12):1581-9. doi: 10.3109/02699052.2014.942371. Epub 2014 Aug 14.
This study investigated the validity of the DEX-Questionnaire (both completed by patients, DEX-Self and by therapists, DEX-TH), included in the Behavioural Assessment of the Dysexecutive Syndrome (BADS), at identifying differences in the severity of dysexecutive symptoms according to lesion location. It also examined the strength of associations of the DEX-Self and the DEX-TH reports with the sub-tests of the BADS as well as two other real-life executive tasks, the Everyday Description Task and the Twenty Question Test.
This study compared 30 patients with anterior lesions (AL) to 22 patients with posterior lesions (PL). Twenty-nine healthy participants and their relatives were included as controls.
Significant group differences were found only on the DEX-TH, but not on the DEX-Self, indicating poor insight in patients with AL. The DEX-TH were revealed accurate in detecting more severe dysexecutive symptoms in the AL group. Furthermore, only the DEX-TH reportings were significantly correlated with the above executive tests. Multiple regression analysis showed that the Modified Six Elements Test, a sub-test of the BADS, predicted DEX-TH as accurately as the total BADS.
The DEX-TH reportings and the MSET can provide valuable information about the severity of daily executive dysfunctioning, with implications for cognitive rehabilitation.
本研究调查了执行功能障碍综合征行为评估(BADS)中包含的DEX问卷(由患者完成的DEX-自我问卷和由治疗师完成的DEX-TH问卷)在根据病变位置识别执行功能障碍症状严重程度差异方面的有效性。研究还检验了DEX-自我问卷和DEX-TH问卷报告与BADS子测试以及另外两项现实生活中的执行任务(日常描述任务和二十问测试)之间的关联强度。
本研究将30例有前部病变(AL)的患者与22例有后部病变(PL)的患者进行了比较。纳入29名健康参与者及其亲属作为对照。
仅在DEX-TH问卷上发现了显著的组间差异,而在DEX-自我问卷上未发现,这表明AL组患者的自知力较差。DEX-TH问卷在检测AL组中更严重的执行功能障碍症状方面显示出准确性。此外,只有DEX-TH问卷报告与上述执行测试显著相关。多元回归分析表明,BADS的一个子测试——改良六元素测试(MSET)对DEX-TH问卷的预测与整个BADS一样准确。
DEX-TH问卷报告和MSET可以提供有关日常执行功能障碍严重程度的有价值信息,对认知康复具有重要意义。