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智力残疾青少年和青年的代谢组学(人体测量学和生物化学)指标与代谢综合征

Metabolomic (anthropometric and biochemical) indexes and metabolic syndrome in adolescents and young adults with intellectual disabilities.

作者信息

Ramos-Jiménez Arnulfo, Hernández-Torres Rosa Patricia, Wall-Medrano Abraham, Villalobos-Molina Rafael

机构信息

Department of Health Sciences, Autonomous University of Ciudad Juarez, Anillo Envolvente del PRONAF y Estocolmo s/n, Ciudad Juárez 32310, Chihuahua, Mexico.

School of Sciences of Physical Culture, Autonomous University of Chihuahua, Ciudad Juárez, Chihuahua, Mexico.

出版信息

Res Dev Disabil. 2014 Nov;35(11):2987-92. doi: 10.1016/j.ridd.2014.07.050. Epub 2014 Aug 12.

DOI:10.1016/j.ridd.2014.07.050
PMID:25124697
Abstract

The aim of the present study was to describe the use of combination of international standardized anthropometric parameters, along with biochemical parameters (metabolomic indexes) to identify metabolic syndrome (MetS), in persons with intellectual disabilities. We conducted a cross-sectional study of 42 adolescents and young adults with intellectual disabilities (aged 13-30years) who attend special schools in Ciudad Juárez, Chihuahua, México. The study included anthropometric (using the International Society for the Advancement of Kineanthropometry recommendations) and biochemical measures, and their combinations as metabolomic-indexes, that can significantly predict MetS occurrence in this vulnerable population. Waist circumference (WC) and relaxed arm circumference, both adjusted for height, have the highest correlation with MetS (R2=0.23-0.47, p<0.01). Besides body mass index (BMI) and WC we propose other indicators such as, skinfolds, hip circumference and relaxed arm circumference, all of them adjusted by height in order to better define the presence of MetS in persons with intellectual disabilities.

摘要

本研究的目的是描述如何使用国际标准化人体测量参数与生化参数(代谢组学指标)相结合,来识别智障人士的代谢综合征(MetS)。我们对42名年龄在13至30岁之间、就读于墨西哥奇瓦瓦州华雷斯城特殊学校的智障青少年和青年成年人进行了一项横断面研究。该研究包括人体测量(采用国际运动人体测量学促进协会的建议)和生化测量,以及它们作为代谢组学指标的组合,这些指标可以显著预测这一弱势群体中代谢综合征的发生。腰围(WC)和放松时的上臂围,两者均根据身高进行了调整,与代谢综合征的相关性最高(R2 = 0.23 - 0.47,p < 0.01)。除了体重指数(BMI)和腰围,我们还提出了其他指标,如皮褶厚度、臀围和放松时的上臂围,所有这些指标均根据身高进行了调整,以便更好地确定智障人士中代谢综合征的存在情况。

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Is body mass index (BMI) or body adiposity index (BAI) a better indicator to estimate body fat and selected cardiometabolic risk factors in adults with intellectual disabilities?
体质指数(BMI)或身体脂肪指数(BAI)是否更能评估成年智障人士的体脂肪和部分心血管代谢风险因素?
BMC Cardiovasc Disord. 2021 Mar 2;21(1):119. doi: 10.1186/s12872-021-01931-9.