Usmani Sharjeel, Alshammari Alshaima
Department of Nuclear Medicine, Faisal Bin Sultan Center, Sufat, Kuwait.
Mubarak Al-Kabeer Hospital, Sufat, Kuwait.
World J Nucl Med. 2013 May;12(2):76-8. doi: 10.4103/1450-1147.136699.
(111)In-pentetreotide [(111)In-octreoscan] is the most widely used radiolabeled somatostatin analog for evaluating neuroendocrine tumor overexpression of somatostatin receptors. False-positives studies of somatostatin receptor scintigraphy have been reported and often the cause is unexplained but assumed to be due to high number of somatostatin receptors in other pathologies. Causes of false-positives include visualization of the gallbladder, nasal mucosa and pulmonary hilar areas in respiratory infections, thyroid abnormalities, accessory spleens, recent Cerebrovascular accidents (CVA's) and activity at the site of a recent surgical incision. In infection or inflammation the cause of false-positive uptake is probably the result of tracer binding by somatostatin receptors on the inflammatory leukocytes. In this case report, we report, a 44-year-old male patient with false-positive (111)In-pentetreotide uptake due to gastritis.
铟-喷替肽（铟-奥曲肽扫描）是用于评估神经内分泌肿瘤生长抑素受体过表达的最广泛使用的放射性标记生长抑素类似物。生长抑素受体闪烁扫描的假阳性研究已有报道，其原因通常不明，但推测是由于其他病理情况下生长抑素受体数量较多。假阳性的原因包括胆囊显影、呼吸道感染时鼻黏膜和肺门区显影、甲状腺异常、副脾、近期脑血管意外（CVA）以及近期手术切口部位的放射性活性。在感染或炎症中，假阳性摄取的原因可能是炎症白细胞上的生长抑素受体与示踪剂结合的结果。在本病例报告中，我们报告了一名44岁男性患者，因胃炎导致铟-喷替肽摄取出现假阳性。
