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[接受门诊培美曲塞维持治疗的非小细胞肺癌患者生活质量相关因素分析]

[Analysis of factors associated with the quality of life in patients with non-small cell lung cancer who received outpatient pemetrexed maintenance therapy].

作者信息

Ishiura Yoshihisa, Shiba Yasutaka, Ikeda Hideko, Terasaki Yasushi, Hinoue Yoshinobu, Ishida Youichi, Hayase Hideko, Maruyama Kazumi, Hamada Mayumi, Obata Chiemi, Ishikawa Mika, Hirokami Kazunori, Kasahara Kazuo, Fujimura Masaki

机构信息

Dept. of Clinical Oncology,Toyama City Hospital.

出版信息

Gan To Kagaku Ryoho. 2014 Jun;41(6):761-4.

Abstract

Increasing number of patients with advanced non-small cell lung cancer are receiving outpatient maintenance chemotherapy. It is very important to maintain these patients' quality of life(QOL). Pemetrexed has been reported to be an effective maintenance chemotherapy. However, its effects on the QOL of patients with non-small cell lung cancer who are undergoing outpatient maintenance chemotherapy are unknown; therefore, we conducted this study. To investigate factors that influence the QOL of these patients, we provided a QOL questionnaire,"The QOL Questionnaire for Cancer Patients Treated with Anticancer Drugs(QOL-ACD)"to 7 patients with non-small cell lung cancer. The medical factors related to the overall QOL scores, as well as other categories indicating"activity","physical condition","psychological condition","social relationship", and"face scale", were analyzed. No significant reductions in any of the factors were observed in this study.

摘要

越来越多的晚期非小细胞肺癌患者正在接受门诊维持化疗。维持这些患者的生活质量(QOL)非常重要。据报道培美曲塞是一种有效的维持化疗药物。然而,其对正在接受门诊维持化疗的非小细胞肺癌患者生活质量的影响尚不清楚;因此,我们开展了这项研究。为了调查影响这些患者生活质量的因素,我们向7例非小细胞肺癌患者提供了一份生活质量问卷,即“抗癌药物治疗癌症患者生活质量问卷(QOL-ACD)”。分析了与总体生活质量评分相关的医学因素,以及表明“活动”、“身体状况”、“心理状况”、“社会关系”和“面部量表”的其他类别。在本研究中未观察到任何因素有显著降低。

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