一项在中国 13 家医院进行的抗生素使用多中心时点调查。
A multicenter point-prevalence survey of antibiotic use in 13 Chinese hospitals.
机构信息
Department of Infection Control, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, PR China; Centre of Health Administration and Development Study, Hubei University of Medicine, Shiyan 442000, PR China.
Department of Infection Control, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, PR China.
出版信息
J Infect Public Health. 2015 Jan-Feb;8(1):55-61. doi: 10.1016/j.jiph.2014.07.001. Epub 2014 Aug 14.
BACKGROUND
The use of antibiotics is considered a major determinant of the development of resistance in organisms. This study assessed current patterns of antibiotic prescription and provides background for quality improvement in general hospitals in Hubei, China.
METHODS
A point-prevalence study was performed in November 2008. All inpatients on the day of the survey were included in the analysis.
RESULTS
On the day of the study, 6904 patients (56%) were receiving antibiotic therapy; the highest rate occurred in the ICU (90%), and the lowest occurred in the medical wards (39%). The most commonly used antibiotics were β-lactam antibiotics, including cephalosporins (40%) and piperacillin (19%), followed by fluoroquinolones (14%).
CONCLUSIONS
Our data indicated a high rate of antibiotic use in Chinese hospitals. These findings suggest important areas for intervention and the implementation of antibiotic stewardship policies in Chinese hospitals. A multi-faceted strategy should be implemented at the national level in China and should include education, regulation, and greater financial support from the government.
背景
抗生素的使用被认为是导致生物体产生耐药性的主要因素。本研究评估了目前抗生素处方的模式，并为中国湖北省综合医院的质量改进提供了背景。
方法
2008 年 11 月进行了一项时点患病率研究。调查当天所有住院患者均纳入分析。
结果
研究当天，6904 名患者（56%）正在接受抗生素治疗；使用率最高的是 ICU（90%），最低的是内科病房（39%）。最常用的抗生素是β-内酰胺类抗生素，包括头孢菌素（40%）和哌拉西林（19%），其次是氟喹诺酮类（14%）。
结论
我们的数据表明中国医院抗生素使用率很高。这些发现表明中国医院需要在干预和实施抗生素管理政策方面有重要的切入点。中国应在国家层面实施多方面的策略，包括教育、监管和政府提供更多的财政支持。
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