Department of Chemical Sciences, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
Carbohydr Polym. 2014 Nov 4;112:6-9. doi: 10.1016/j.carbpol.2014.05.063. Epub 2014 Jun 2.
Polysaccharides have received a great deal of attention from, for example, the food, cosmetic and pharmaceutical industries. Their conformations (flexibility/stiffness) span a wide range of conformational flexibilities with large hydrated volumes, these properties are important in relation to polysaccharide structure-function relationships. Perhaps the simplest parameter available to estimate the dilute solution conformation of polysaccharides is the Smidsrød-Haug stiffness parameter (B) where the stiffness of polyelectrolytes can be estimated by measuring the intrinsic viscosity at a number of different ionic strengths. In this paper we propose an alternative method for estimating the Smidsrød-Haug stiffness parameter (B) using the ionic strength dependency of zeta potential. For this purpose we have studied a number of different polysaccharides.
多糖已受到食品、化妆品和制药等行业的广泛关注。其构象（柔韧性/刚性）具有很大的水合体积，跨越了广泛的构象柔韧性范围，这些性质与多糖的结构-功能关系有关。也许最简单的参数可用于估计多糖在稀溶液中的构象是 Smidsrød-Haug 刚性参数（B），通过在多个不同离子强度下测量特性粘度可以估计聚电解质的刚性。在本文中，我们提出了一种使用 ζ 电位的离子强度依赖性来估计 Smidsrød-Haug 刚性参数（B）的替代方法。为此，我们研究了许多不同的多糖。
