一种使用声诺维增强超声检测胰腺移植术后移植物血栓形成的新型筛查试验。
A novel screening test for detecting graft thrombosis after pancreatic transplantation using contrast-enhanced ultrasonography with sonazoid.
作者信息
Ito T, Kenmochi T, Nishikawa T, Maruyama M, Kusaka M, Sasaki H, Asano T, Matsubara H, Hoshinaga K
机构信息
Department of Organ Transplant Surgery, Fujita Health University, School of Medicine, Aichi, Japan.
Department of Organ Transplant Surgery, Fujita Health University, School of Medicine, Aichi, Japan.
出版信息
Transplant Proc. 2014 Jul-Aug;46(6):1917-9. doi: 10.1016/j.transproceed.2014.05.071.
Pancreatic graft thrombosis is the primary cause of nonimmunologic graft loss, with an incidence ranging from 5% to 15%. Therefore, developing a screening test to detect graft thrombosis after pancreatic transplantation is important. We created a screening test to assess graft thrombosis after pancreatic transplantation using contrast-enhanced ultrasonography (CEUS) with Sonazoid in addition to Doppler ultrasonography. A total of seven patients were examined using CEUS after undergoing pancreatic transplantation. All patients were observed to have a clear blood flow from the horizontal region to the peripheral region of the splenic vein in the pancreatic graft, and only one of the seven patients exhibited a blood flow in the horizontal portion of the splenic vein on Doppler ultrasonography performed immediately after pancreatic transplantation. Results from CEUS with Sonazoid showed the blood flow in the splenic vein and parenchyma of the pancreatic graft in detail, despite the slow and lateral blood flow in the splenic vein of the pancreatic graft immediately after transplantation.
胰腺移植血栓形成是非免疫性移植物丢失的主要原因，发生率在5%至15%之间。因此，开发一种筛查试验以检测胰腺移植后的移植物血栓形成非常重要。我们创建了一种筛查试验，除了使用多普勒超声外，还使用声诺维增强超声（CEUS）来评估胰腺移植后的移植物血栓形成。共有7例患者在接受胰腺移植后接受了CEUS检查。所有患者在胰腺移植物的脾静脉中均观察到从水平区域到周边区域的清晰血流，而在胰腺移植后立即进行的多普勒超声检查中，7例患者中只有1例在脾静脉的水平部分显示出血流。声诺维增强超声的结果详细显示了胰腺移植物脾静脉和实质中的血流，尽管移植后胰腺移植物脾静脉中的血流缓慢且呈侧向。
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