Zeng Fanjun, Guan Zhaojie, Wu Zhenghua, Ming Changsheng, Chen Hua, Wang Zhenxing, Chen Zhonghua
Shanxi Bethune Hospital (Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University), Taiyuan, China; Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology (Key Laboratory of Organ Transplantation, Ministry of Education; NHC Key Laboratory of Organ Transplantation; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences), Wuhan, China.
Shanxi Bethune Hospital (Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University), Taiyuan, China.
Transplant Proc. 2024 Mar;56(2):456-458. doi: 10.1016/j.transproceed.2024.01.046. Epub 2024 Feb 5.
In classic pancreatic transplantation, the splenic artery and vein are ligated at the tail of the pancreas graft. This leads to slowed blood flow in the splenic vein and may cause thrombosis and graft loss. In this study, a patient received a pancreas after kidney transplantation. A modified surgical technique was used in the pancreatic graft preparation. The donor splenic artery and vein were anastomosed end to end at the tail of the pancreas. The splenic artery near the anastomosis was partially ligated, and an effective diameter of 2 mm was reserved to limit arterial blood pressure and flow. The patient recovered very well. Contrasted computed tomography scans on days 11 and 88 after pancreas transplantation indicated sufficient backflow of the splenic vein. We believe that this procedure may avoid the risk of splenic vein thrombosis after pancreas transplantation. This modified technique has not been reported in clinical cases previously and may help reduce the risk of thrombosis after pancreas transplantation.
在经典的胰腺移植中，脾动脉和脾静脉在胰腺移植物的尾部被结扎。这会导致脾静脉血流减慢，并可能引起血栓形成和移植物丢失。在本研究中，一名患者在肾移植后接受了胰腺移植。在胰腺移植物制备过程中采用了改良的手术技术。供体脾动脉和脾静脉在胰腺尾部端端吻合。吻合口附近的脾动脉部分结扎，保留2毫米的有效直径以限制动脉血压和血流。患者恢复得非常好。胰腺移植后第11天和第88天的计算机断层扫描显示脾静脉回流充足。我们认为，该手术可避免胰腺移植后脾静脉血栓形成的风险。这种改良技术此前尚未见临床病例报道，可能有助于降低胰腺移植后血栓形成的风险。
