头颈癌患者营养不良的相关因素。
Factors associated with malnutrition in patients with head and neck cancer.
作者信息
Takenaka Yukinori, Yamamoto Masashi, Nakahara Susumu, Yamamoto Yoshifumi, Yasui Toshimichi, Hanamoto Atshushi, Takemoto Norihiko, Fukusumi Takahito, Michiba Takahiro, Cho Hironori, Inohara Hidenori
机构信息
Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine , Suita, Osaka , Japan.
出版信息
Acta Otolaryngol. 2014 Oct;134(10):1079-85. doi: 10.3109/00016489.2014.906750. Epub 2014 Aug 18.
CONCLUSIONS
Comorbidities as well as T classification were the primary determinants for the nutritional status of patients with head and neck cancer.
OBJECTIVES
We aimed to elucidate the underlying conditions of malnutrition in patients with head and neck cancer.
METHODS
We retrospectively reviewed 726 patients diagnosed with head and neck cancer between 2004 and 2013. Associations between malnutrition and clinical parameters were assessed using univariate and multivariate analyses.
RESULTS
Median body mass index was 21.5 (range 11.6-38.0). According to World Health Organization criteria, the nutritional status of these patients was classified into four groups: underweight (18%), normal (63%), overweight (17%), and obese (1%). Comorbidities were detected in 40% of patients. Multivariate analysis revealed the following factors to be independent factors associated with malnutrition: advanced T stage, metachronous cancer, collagen disease, gastrointestinal disease, and pulmonary disease.
结论
合并症以及T分期是头颈癌患者营养状况的主要决定因素。
目的
我们旨在阐明头颈癌患者营养不良的潜在状况。
方法
我们回顾性分析了2004年至2013年间诊断为头颈癌的726例患者。使用单因素和多因素分析评估营养不良与临床参数之间的关联。
结果
中位体重指数为21.5（范围11.6 - 38.0）。根据世界卫生组织标准，这些患者的营养状况分为四组：体重过轻（18%）、正常（63%）、超重（17%）和肥胖（1%）。40%的患者检测到合并症。多因素分析显示以下因素是与营养不良相关的独立因素：晚期T分期、异时性癌、胶原病、胃肠疾病和肺部疾病。
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