Szyszkowicz M, Shutt R, Kousha T, Rowe B H
Population Studies Division, Health Canada, Ottawa, ON, Canada.
Clin Otolaryngol. 2014 Dec;39(6):345-51. doi: 10.1111/coa.12296.
This study aimed to evaluate the association between outdoor ambient air pollution and emergency department (ED) visits for epistaxis.
Cross-sectional study, case-crossover design.
ED visit data were obtained for Edmonton, Alberta, Canada, for a period of 10 years starting 1 April 1992 and ending March 31st of 2002. The data on ED visits were supplied by Capital Health for the five major acute care hospitals in the Edmonton area.
The analysis was performed for the population as a whole (N = 15 038) and split by sex: males (N = 8587) and females (N = 6451).
We explored associations between ambient concentrations of air pollutants (CO, NO2 , SO2 , O3 , PM10 , PM2.5 ) lagged by 0-4 days and ED visits for epistaxis in Edmonton, Alberta, Canada.
Odds ratios (ORs) and their 95% confidence intervals (CI) were reported for an increase in an interquartile range (IQR) of pollutant concentration. We obtained positive and statistically significant results for all patients with epistaxis; exposure to O3 with IQR = 14 ppb, OR = 1.05 (95% CI: 1.00-1.09, lag 0), and for males (age < 25 years), OR = 1.16 (1.03-1.30), lag 4; and to PM10 with IQR = 15 μg/m(3) , OR = 1.02 (1.00-1.05, lag 3). These results were stronger for older (age > 24 years) females.
These findings suggest that there may be an association between air pollutant exposure, specifically ozone and PM10 , and the number of ED visits for epistaxis.
本研究旨在评估室外环境空气污染与鼻出血急诊就诊之间的关联。
横断面研究,病例交叉设计。
获取了加拿大艾伯塔省埃德蒙顿市1992年4月1日至2002年3月31日期间10年的急诊就诊数据。急诊就诊数据由首都健康机构提供,涉及埃德蒙顿地区的五家主要急症护理医院。
对全体人群(N = 15038)进行分析,并按性别分为男性(N = 8587)和女性(N = 6451)。
我们探讨了滞后0 - 4天的空气污染物(一氧化碳、二氧化氮、二氧化硫、臭氧、PM10、PM2.5)环境浓度与加拿大艾伯塔省埃德蒙顿市鼻出血急诊就诊之间的关联。
报告了污染物浓度增加一个四分位间距(IQR)时的优势比(OR)及其95%置信区间(CI)。对于所有鼻出血患者,我们都获得了阳性且具有统计学意义的结果;臭氧浓度IQR = 14 ppb时,OR = 1.05(95% CI:1.00 - 1.09,滞后0天),对于男性(年龄<25岁),OR = 1.16(1.03 - 1.30),滞后4天;PM10浓度IQR = 15 μg/m³时,OR = 1.02(1.00 - 1.05,滞后3天)。这些结果在年龄较大(>24岁)的女性中更为明显。
这些发现表明,空气污染物暴露,特别是臭氧和PM10,与鼻出血急诊就诊次数之间可能存在关联。