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80例福尼埃坏疽病例的经验及“创伤”作为病因发病机制中的触发因素

Experience of 80 cases with Fournier's gangrene and "trauma" as a trigger factor in the etiopathogenesis.

作者信息

Eskitaşcıoğlu Teoman, Özyazgan Irfan, Coruh Atilla, Günay Galip K, Altıparmak Mehmet, Yontar Yalcin, Doğan Fatih

机构信息

Department of Plastic Reconstructive and Aesthetic Surgery, Erciyes University Faculty of Medicine, Kayseri, Turkey.

出版信息

Ulus Travma Acil Cerrahi Derg. 2014 Jul;20(4):265-74. doi: 10.5505/tjtes.2014.67670.

Abstract

BACKGROUND

The purpose of the present study was to retrospectively analyze the patients' data presented with Fournier's gangrene (FG), to compare obtained data with the literature and to investigate the role of "trauma" in the etiopathogenesis.

METHODS

A retrospective study was conducted on 126 patients with FG that consulted to our department.

RESULTS

There were 76 male and four female patients. The mean age of the patients was 53.5±13.6 years. The most common presentation of patients was swelling (n=74). The scrotum has been shown to be the most commonly affected area in the patients (n=75). Diabetes mellitus was the leading predisposing factor and trauma was the leading responsible cause for FG. Escherichia coli was the most frequently identified microorganism (n=43, 53.75%). Primary closure was the most common technique used for all patients. Three patients exhibited a mortal course due to sepsis and multi-organ failure.

CONCLUSION

FG still has a high mortality rate. Rapid and correct diagnosis of the disease can avoid inappropriate or delayed treatment and even death of the patient. The healthcare professionals should be aware that any trauma in the perineal region could lead to FG.

摘要

背景

本研究的目的是回顾性分析患有福尼尔坏疽(FG)患者的数据,将获得的数据与文献进行比较,并研究“创伤”在病因发病机制中的作用。

方法

对到我院就诊的126例FG患者进行回顾性研究。

结果

有76例男性患者和4例女性患者。患者的平均年龄为53.5±13.6岁。患者最常见的表现是肿胀(n=74)。阴囊是患者中最常受累的部位(n=75)。糖尿病是主要的易感因素,创伤是FG的主要致病原因。大肠埃希菌是最常鉴定出的微生物(n=43,53.75%)。一期缝合是所有患者最常用的技术。3例患者因败血症和多器官衰竭而死亡。

结论

FG的死亡率仍然很高。对该病进行快速、正确的诊断可以避免不适当或延迟的治疗,甚至避免患者死亡。医护人员应意识到会阴部的任何创伤都可能导致FG。

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