Sockkalingam Vigneswara Srinivasan, Subburayan Elankumar, Velu Elango, Rajashekar Sujith Tumkur, Swamy Anusha Mruthyunjaya
Department of Surgery, Coimbatore Medical College, Coimbatore, India.
Department of Pharmacology, Narayana Medical College, Nellore, India.
Pan Afr Med J. 2018 Oct 12;31. doi: 10.11604/pamj.2018.31.110.15495. eCollection 2018.
Fournier's gangrene (FG) is a fulminant necrotizing fasciitis of the perineum and genitalia. The objective of this study was to study the etiology and microbiology associated with FG and to study the debridement and reconstructive procedures required in these patients.
This was a prospective follow up study conducted from September 2011 to November 2012 at Coimbatore medical college hospital, Coimbatore, India. Patients presenting to the outpatient department and emergency department with the clinical diagnosis of FG were included in the study.
A total of 34 patients were studied in the study period. The mean age of presentation in years was 50±11.13. The male to female ratio was 33:1. The source of the infection was most commonly anorectal. Diabetes mellitus was the most common co morbid factor associated. Most commonly the disease was polymicrobial with escherichia coli being the commonest grown organism. The average number of wound debridement required was 2.9±1.42. Primary closure of the scrotal skin defect was the most common reconstructive procedure performed. Mortality associated with the disease in our series was 11.8%.
Although FG is a relatively rare disease, it is still prevalent in Indian population. Incidence of FG in HIV patients is high, even though it is not the commonest of the co morbid condition. The mortality can be kept to minimal with aggressive medical and surgical management. Extensive raw area following the infection and wound debridement can be managed by simple reconstructive procedures with good outcome.
福尼尔坏疽(FG)是一种会阴部和生殖器的暴发性坏死性筋膜炎。本研究的目的是研究与FG相关的病因学和微生物学,并研究这些患者所需的清创和重建手术。
这是一项于2011年9月至2012年11月在印度哥印拜陀市哥印拜陀医学院医院进行的前瞻性随访研究。纳入研究的患者为在门诊和急诊科就诊且临床诊断为FG的患者。
在研究期间共研究了34例患者。就诊时的平均年龄为50±11.13岁。男女比例为33:1。感染源最常见于肛肠部位。糖尿病是最常见的合并症因素。该疾病最常见为多微生物感染,大肠杆菌是最常培养出的微生物。所需的伤口清创平均次数为2.9±1.42次。阴囊皮肤缺损的一期缝合是最常见的重建手术。我们系列中与该疾病相关的死亡率为11.8%。
尽管FG是一种相对罕见的疾病,但在印度人群中仍然普遍存在。FG在HIV患者中的发病率很高,尽管它不是最常见的合并症。通过积极的内科和外科治疗,死亡率可降至最低。感染和伤口清创后形成的大面积创面可通过简单的重建手术进行处理,效果良好。