结节性基底细胞癌综合征的 F-FDG PET/CT 表现：系统评价与 1 例新病例报告。
F-FDG PET/CT findings in nevoid basal cell carcinoma syndrome: a systematic review and a new case report.
机构信息
Department of PET/CT, Qingdao Central Hospital, No 127. SiLiu Nan Street, ShanDong Province, Qingdao City, 266042, China.
Department of Burn and Plastic Surgery, Qingdao Central Hospital, ShanDong Province, Qingdao, 266042, China.
出版信息
BMC Womens Health. 2024 May 28;24(1):310. doi: 10.1186/s12905-024-03145-5.
BACKGROUND
To demonstrate and analyze the F-FDG positron emission tomography/computed tomography (PET/CT) findings in this rare nevoid basal cell carcinoma syndrome (NBCCS).
CASE PRESENTATION
A 71-year-old woman with the left invasive breast cancer was treated with hormone therapy for six months and underwent the F-FDG PET/CT examination for efficacy evaluation. F-FDG PET/CT revealed the improvement after treatment and other unexpected findings, including multiple nodules on the skin with F-FDG uptake, bone expansion of cystic lesions in the bilateral ribs, ectopic calcifications and dilated right ureter. She had no known family history. Then, the patient underwent surgical excision of the all skin nodules and the postoperative pathology were multiple basal cell carcinomas. Finally, the comprehensive diagnosis of NBCCS was made. The patient was still in follow-up. Additionally, we have summarized the reported cases (n = 3) with F-FDG PET/CT from the literature.
CONCLUSIONS
It is important to recognize this syndrome on F-FDG PET/CT because of different diagnoses and therapeutic consequences.
背景
为了展示和分析这种罕见的痣样基底细胞癌综合征（NBCCS）的 F-FDG 正电子发射断层扫描/计算机断层扫描（PET/CT）表现。
病例介绍
一名 71 岁女性患有左侧浸润性乳腺癌，接受了六个月的激素治疗，并进行了 F-FDG PET/CT 检查以评估疗效。F-FDG PET/CT 显示治疗后有所改善，同时还发现了其他意外发现，包括皮肤多处结节伴有 F-FDG 摄取、双侧肋骨囊性病变的骨膨胀、异位钙化和右侧输尿管扩张。患者无已知家族史。随后，患者接受了所有皮肤结节的手术切除，术后病理为多发性基底细胞癌。最终，综合诊断为 NBCCS。患者仍在随访中。此外，我们还总结了文献中报道的 3 例（n=3）伴有 F-FDG PET/CT 的病例。
结论
在 F-FDG PET/CT 上识别出这种综合征很重要，因为它会导致不同的诊断和治疗后果。
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