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[人类免疫缺陷病毒感染过程中的脑电图检查结果]

[EEG findings during the course of HIV infection].

作者信息

Schnurbus R, Könneke J, Friedrich-Jännicke B, Flessenkämper S, Bienzle U, Girke W

机构信息

Abteilung für Neurologie, Klinikums Rudolf Virchow, Freien Universität Berlin.

出版信息

EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1989 Dec;20(4):238-42.

PMID:2514082
Abstract

Clinical neurological complications in HIV-infection (Human Immunodeficiency Virus) are seen in later stages of the disease. EEGs of 186 patients in different stages of HIV-infection and of 44 HIV-seronegative volunteers (total of 566 recordings) were evaluated visually; this revealed an increasing appearance of CNS-dysfunction (slowing of background activity, focal and diffuse CNS-dysfunction) associated with a progression of the disease. Slowing of background activity was already found in early stages of HIV-infection. Additional focal and diffuse changes in the electrical activity of the brain are also seen with progression of the infection (LAS/ARC-AIDS). The correlation between these electroencephalographic changes and HIV related clinical symptoms are non specific however, EEG recordings can be a valuable aid in following CNS-dysfunction during the course of HIV-infection.

摘要

人类免疫缺陷病毒(HIV)感染的临床神经并发症出现在疾病后期。对186例处于不同HIV感染阶段的患者和44名HIV血清阴性志愿者的脑电图(共566份记录)进行了视觉评估;结果显示,随着疾病进展,中枢神经系统功能障碍(背景活动减慢、局灶性和弥漫性中枢神经系统功能障碍)越来越多地出现。背景活动减慢在HIV感染早期就已出现。随着感染进展(从淋巴结病相关综合征/艾滋病相关复合征到艾滋病),大脑电活动还会出现额外的局灶性和弥漫性变化。然而,这些脑电图变化与HIV相关临床症状之间的相关性并不具有特异性,不过,脑电图记录在跟踪HIV感染过程中的中枢神经系统功能障碍方面可能是一项有价值的辅助手段。

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