Tonk Gyaneshwar, Kumar Anish, Gupta Amit
Department of Orthopaedics, LLRM Medical College, Meerut, Uttar Pradesh, India.
Indian J Orthop. 2014 Jul;48(4):390-3. doi: 10.4103/0019-5413.136260.
Platelet rich plasma (PRP) extract has shown to be a general stimulation for repair and currently used widely in various sports injury. A prospective observational study was done to assess the efficacy of autologous PRP injection in lateral epicondylitis of elbow, and compare the result with low level laser therapy.
The trial was conducted at a tertiary care center for a period of 2 years. Eighty-one patients with chronic lateral epicondylitis were divided into two groups. PRP group (n = 39) and laser therapy group (n = 42). The primary analysis included Nirschl pain score, local tenderness, pain on wrist extension, grip strength, elbow swelling were clinically assessed at different interval of followup (minimum followup: 52 weeks) and; clinical and functional outcome evaluated at final followup. The statistical analysis were done.
The mean Nirschl pain score decreased significantly from baseline in PRP when compared with low level laser therapy (P ≤ 0.05).
Treatment of patients with chronic lateral epicondylitis with PRP extract reduced pain and significantly increased function, exceeding the effect of low level laser therapy on long term followup. Low-level laser therapy is better in the short term period, but on long term followup injection PRP therapy is better than laser therapy in lateral epicondylitis.
富含血小板血浆(PRP)提取物已被证明是一种促进修复的通用刺激物,目前广泛应用于各种运动损伤。进行了一项前瞻性观察研究,以评估自体PRP注射治疗肘部外侧上髁炎的疗效,并将结果与低强度激光治疗进行比较。
该试验在一家三级护理中心进行,为期2年。81例慢性肘部外侧上髁炎患者分为两组。PRP组(n = 39)和激光治疗组(n = 42)。主要分析包括在不同随访间隔(最短随访:52周)时临床评估Nirschl疼痛评分、局部压痛、腕关节伸展时疼痛、握力、肘部肿胀情况;并在最终随访时评估临床和功能结果。进行了统计分析。
与低强度激光治疗相比,PRP组的平均Nirschl疼痛评分从基线显著降低(P≤0.05)。
用PRP提取物治疗慢性肘部外侧上髁炎患者可减轻疼痛并显著改善功能,在长期随访中超过了低强度激光治疗的效果。低强度激光治疗在短期内效果较好,但在长期随访中,PRP注射治疗肘部外侧上髁炎优于激光治疗。