Layoun Nelly, Saleh Nadine, Barbour Bernadette, Awada Sanaa, Rachidi Samar, Al-Hajje Amal, Bawab Wafaa, Waked Mirna, Salameh Pascale
Doctoral School of Sciences and Technologies, Lebanese University , Beirut , Lebanon .
Inhal Toxicol. 2014 Aug;26(10):620-7. doi: 10.3109/08958378.2014.945106.
Smoking is known to have physiological effects on biological systems. The purpose of this study is to evaluate acute and chronic effects on pulmonary functions and cardiovascular indices of waterpipe (WP) smoking in real life circumstances.
Three groups were included in the study: non-smokers (N = 42), WP smokers (N = 42) and cigarette smokers (N = 48). A questionnaire was completed for each participant, in addition to pulmonary function [forced expiratory volume at 1 s (FEV1), 6 s (FEV6), percentage of FEV1/FEV6], and cardiovascular [diastolic blood pressure (DBP), systolic blood pressure (SBP) and heart rate (HR)] measures, taken before and after smoking.
Mean values of FEV1, FEV6, FEV1/FEV6, DBP and SBP in WP and cigarette smokers were very close. However, WP smoking significantly increased HR compared to cigarette smokers (p = 0.007); duration of smoking, age at first WP and quantity of smoking affected pulmonary function and cardiovascular values. In the subgroup of WP smokers, DBP was acutely increased by a larger WP size (p = 0.011), while the FEV6 was acutely increased by a smaller WP size (p = 0.045).
WP smoking affected the cardiovascular system more than cigarette smoking, while it had similar effects on pulmonary function.
众所周知，吸烟会对生物系统产生生理影响。本研究的目的是评估在现实生活环境中，水烟吸食对肺功能和心血管指标的急性和慢性影响。
本研究纳入三组：非吸烟者（N = 42）、水烟吸食者（N = 42）和卷烟吸烟者（N = 48）。除了肺功能[1秒用力呼气量（FEV1）、6秒用力呼气量（FEV6）、FEV1/FEV6百分比]和心血管指标[舒张压（DBP）、收缩压（SBP）和心率（HR）]测量值外，还为每位参与者填写了一份问卷，这些测量值在吸烟前后进行采集。
水烟吸食者和卷烟吸烟者的FEV1、FEV6、FEV1/FEV6、DBP和SBP的平均值非常接近。然而，与卷烟吸烟者相比，吸食水烟显著增加了心率（p = 0.007）；吸烟持续时间、首次吸食水烟的年龄和吸烟量影响肺功能和心血管值。在水烟吸食者亚组中，较大尺寸的水烟会使DBP急性升高（p = 0.011），而较小尺寸的水烟会使FEV6急性升高（p = 0.045）。
吸食水烟对心血管系统的影响大于吸食卷烟，而对肺功能的影响相似。
