Randau T M, Gravius S, Nüssler A
Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
Siegfried Weller Institut für Unfallmedizinische Forschung, BG Unfallklinik, Eberhard-Karls Universität Tübingen.
Z Orthop Unfall. 2014 Aug;152(4):320-7. doi: 10.1055/s-0034-1382867. Epub 2014 Aug 21.
Over the last few years, numerous new treatment methods have been developed for musculoskeletal diseases. Some of these new methods are based on the targeted use of stem cells to initiate healing processes, to compensate for deficits or to activate the regeneration of tendons, muscles, bones and cartilage. This goal can be achieved through the direct use of stem cells on or in a carrier material or through a combination with tissue engineering. In this article, we give a short overview of the possible fields of application of inducible pluripotent haematopoietic, and adult stem cells as well as on their use in musculoskeletal tissue. Furthermore, we provide a summary of the current legal situation concerning the application of stem cells in humans.
在过去几年中，已经开发出许多用于肌肉骨骼疾病的新治疗方法。其中一些新方法基于有针对性地使用干细胞来启动愈合过程、弥补缺陷或激活肌腱、肌肉、骨骼和软骨的再生。这一目标可以通过在载体材料上或载体材料中直接使用干细胞，或通过与组织工程相结合来实现。在本文中，我们简要概述了诱导多能造血干细胞和成人干细胞可能的应用领域，以及它们在肌肉骨骼组织中的用途。此外，我们还总结了目前干细胞在人体应用方面的法律状况。
