Döbrönte Z
II. Medizinischen Abteilung des Markusovszky-Krankenhauses Szombathely.
Z Gesamte Inn Med. 1989 Oct 15;44(20):621-6.
The pathophysiology, diagnosis and therapy of biliary motility disorders are surveyed on the basis of the literature and own experience. Bile duct dyskinesia is clinically characterised by pain of biliary and sometimes pancreatic type evoked by meal or psychogenic influence. A prerequisite of the diagnosis is the exclusion of any organic origin of the complaints. In the routine clinical practice Oddi's sphincter dyskinesia can be diagnosed by the simultaneous assessment of the response to a provocation test and the therapeutic effect of a sphincter-relaxant, e.g. nitroglycerine. For differentiating between papillary stenosis and dismotility the endoscopic manometry and radiopharmacological methods are of greatest value. The cystic duct dyskinesia can be recognized with the help of cholecystokinetic provocation test and on the basis of therapeutic response to nitrite derivates. The therapy of the biliary dyskinesia includes influence on the evoking dietetic and psychic factors and administration of long-acting sphincter relaxants as well. In failure of the conservative therapy the complaints caused by Oddi's sphincter dyskinesia and cystic duct dyskinesia can be abolished by endoscopic or surgical sphincterotomy and cholecystectomy, respectively.
基于文献和自身经验,对胆道运动障碍的病理生理学、诊断和治疗进行综述。胆管运动障碍的临床特征是进食或心理因素诱发的胆道疼痛,有时是胰腺型疼痛。诊断的前提是排除任何器质性病因导致的症状。在常规临床实践中,奥狄括约肌运动障碍可通过同时评估激发试验的反应和括约肌松弛剂(如硝酸甘油)的治疗效果来诊断。对于鉴别乳头狭窄和运动障碍,内镜测压和放射性药物方法最有价值。胆囊管运动障碍可借助胆囊动力学激发试验并根据对亚硝酸盐衍生物的治疗反应来识别。胆道运动障碍的治疗包括对诱发饮食和心理因素的影响以及使用长效括约肌松弛剂。在保守治疗无效时,奥狄括约肌运动障碍和胆囊管运动障碍引起的症状可分别通过内镜或手术括约肌切开术和胆囊切除术消除。