Tangso Kristian J, Ho Quy Phuong, Boyd Ben J
Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus) 381 Royal Parade, Parkville, Victoria.
Curr Drug Deliv. 2015;12(1):56-62. doi: 10.2174/1567201811666140821112637.
Conventional dosage forms such as tablets, capsules and syrups are prescribed in the normal course of practice. However, concerns about patient preferences and market demands have given rise to the exploration of novel unconventional dosage forms. Among these, confectionery-based dose forms have strong potential to overcome compliance problems. This report will review the availability of these unconventional dose forms used in treating the oral cavity and for systemic drug delivery, with a focus on medicated chewing gums, medicated lollipops, and oral bioadhesive devices. The aim is to stimulate increased interest in the opportunities for innovative new products that are available to formulators in this field, particularly for atypical patient populations.
在常规医疗实践中会开具片剂、胶囊和糖浆等传统剂型。然而,对患者偏好和市场需求的关注引发了对新型非传统剂型的探索。其中,基于糖果的剂型在克服依从性问题方面具有很大潜力。本报告将综述这些用于口腔治疗和全身给药的非传统剂型,重点关注药用口香糖、药用棒棒糖和口腔生物黏附装置。目的是激发人们对该领域配方设计师可获得的创新新产品机会的更多兴趣,特别是针对非典型患者群体。