Natad Ashley, Moser Kathleen, Maiden Jeanne, Kim Son Chae
Wake County Human Services, Raleigh, NC, USA
County of San Diego, TB & Refugee Health Branch, San Diego, CA, USA.
Clin Nurs Res. 2016 Feb;25(1):100-12. doi: 10.1177/1054773814547045. Epub 2014 Aug 20.
This cross-sectional study explored tuberculosis (TB) knowledge, attitudes, practice, and TB interferon-gamma release assay (IGRA) results as the predictor of self-reported poor mental and physical health among HIV-infected persons attending a sexually transmitted diseases clinic (N = 111). The participants correctly responded to only 56.6% of the TB knowledge questions. Most had positive attitudes and would not be ashamed of TB diagnosis. The TB practice was suboptimal with only half having been tested for TB within the past 2 years. Eight percent of the participants had positive IGRA (n = 9). Simultaneous multiple regression models showed that positive IGRA, an indicator of latent TB infection, was the only significant predictor of both poor mental health (p = .006) and physical health days (p = .016). IGRA screening and treatment of latent TB infection in HIV-infected persons could potentially improve their mental and physical health status in addition to reducing the TB reactivation rate.
这项横断面研究探讨了结核病（TB）知识、态度、行为以及结核干扰素-γ释放试验（IGRA）结果，以此作为在一家性传播疾病诊所就诊的HIV感染者自我报告的身心健康不佳的预测指标（N = 111）。参与者对结核病知识问题的正确回答率仅为56.6%。大多数人态度积极，不会因结核病诊断而感到羞耻。结核病防治行为并不理想，过去两年中只有一半人接受过结核病检测。8%的参与者IGRA呈阳性（n = 9）。同时多元回归模型显示，作为潜伏性结核感染指标的IGRA阳性，是心理健康不佳（p = 0.006）和身体健康天数（p = 0.016）的唯一显著预测因素。对HIV感染者进行IGRA筛查和潜伏性结核感染治疗，除了降低结核病复发率外，还可能改善他们的身心健康状况。
