PyBamView：一个基于浏览器的短读序列比对查看应用程序。

PyBamView: a browser-based application for viewing short read alignments.

机构信息

Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, MA 02139 and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, MA 02139 and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, MA 02139 and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

出版信息

Bioinformatics. 2014 Dec 1;30(23):3405-7. doi: 10.1093/bioinformatics/btu565. Epub 2014 Aug 21.

DOI:10.1093/bioinformatics/btu565

PMID:25147359

Abstract

UNLABELLED

Current sequence alignment browsers allow visualization of large and complex next-generation sequencing datasets. However, most of these tools provide inadequate display of insertions and can be cumbersome to use on large datasets. I implemented PyBamView, a lightweight Web application for visualizing short read alignments. It provides an easy-to-use Web interface for viewing alignments across multiple samples, with a focus on accurate visualization of insertions.

AVAILABILITY AND IMPLEMENTATION

PyBamView is available as a standard python package. The source code is freely available under the MIT license at https://mgymrek.github.io/pybamview.

摘要

未加标签

当前的序列比对浏览器允许可视化大型和复杂的下一代测序数据集。然而，这些工具中的大多数提供了不足的插入显示，并且在大型数据集上使用起来很麻烦。我实现了 PyBamView，这是一个用于可视化短读比对的轻量级 Web 应用程序。它提供了一个易于使用的 Web 界面，用于跨多个样本查看比对，重点是准确可视化插入。