多灶性上皮增生：3例报告。

Multifocal epithelial hyperplasia: report of 3 cases.

作者信息

Tehranchinia Zohreh, Mozafari Nikoo, Barikbin Behrooz, Nadji Seyed Alireza

机构信息

Shahid Beheshti University of Medical Sciences.

出版信息

Dermatol Online J. 2014 Aug 17;20(8):13030/qt12p1s5xc.

PMID:25148288

Abstract

Multifocal epithelial hyperplasia (MEH) is a rare disorder characterized by multiple painless discrete and soft flattened papules on the oral mucosa. It is caused by human papilloma virus 13 and 32. The frequency of this disease varies widely from one geographic region to another. Generally it is very rare in Asia. Herein we report 3 Iranian cases with oral lesions, which showed clinical and histopathological characteristics of MEH disease. Two of them were siblings and HPV13 was detected in one of the patients.

摘要

多灶性上皮增生（MEH）是一种罕见的疾病，其特征为口腔黏膜上出现多个无痛性、离散的、柔软扁平的丘疹。它由人乳头瘤病毒13型和32型引起。这种疾病的发病率在不同地理区域差异很大。一般来说，在亚洲非常罕见。在此，我们报告3例伊朗口腔病变病例，其表现出多灶性上皮增生疾病的临床和组织病理学特征。其中2例为兄弟姐妹，1例患者检测出HPV13。