使用γ-谷氨酰-p-氨基苯甲酸作为底物测定血清中γ-谷氨酰转肽酶活性。
The use of gamma-glutamyl-p-aminobenzoic acid as the substrate for determination of gamma-glutamyltranspeptidase activity in blood serum.
作者信息
Szewczuk A, Wellman-Bednawska M
出版信息
Clin Chim Acta. 1978 Mar 1;84(1-2):19-26. doi: 10.1016/0009-8981(78)90471-0.
PMID:25149
Abstract
By the phthaloyl method less toxic and readily soluble gamma-L-glutamyl-p-aminobenzoic acid was synthesized. This substance was used as a substrate for gamma-glutamyltranspeptidase activity assay in blood serum and urine. Close correlation was shown between the results obtained with the new method and with the old one which used gamma-L-glutamyl-p-nitroanilide.
摘要
通过邻苯二甲酰法合成了毒性较小且易溶的γ-L-谷氨酰对氨基苯甲酸。该物质被用作血清和尿液中γ-谷氨酰转肽酶活性测定的底物。新方法与使用γ-L-谷氨酰对硝基苯胺的旧方法所获得的结果之间显示出密切的相关性。
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