Department of Pharmacy, University of Washington, Harborview Medical Center, Seattle, WA.
Department of Pharmacy, University of Washington, Harborview Medical Center, Seattle, WA.
J Am Coll Surg. 2014 Oct;219(4):631-7. doi: 10.1016/j.jamcollsurg.2014.05.014. Epub 2014 Jun 12.
The purpose of this study was to determine the mortality predictive value of two different comorbidity scores, Comorbidity-Polypharmacy Score (CPS) and Charlson scoring system, in a large sample of older trauma patients.
At an urban tertiary care Level I trauma center, trauma patients aged 55 years and older who were initially admitted to critical care were included. This retrospective chart review was conducted at Harborview Medical Center in Seattle, WA. Older trauma patients admitted from January 1, 2010 through December 31, 2010 were screened for inclusion. One-year mortality data were obtained from the Washington State Department of Health. Covariates included age, presence of hypotension, traumatic brain injury, and Injury Severity Score.
Records for 667 older trauma patients were reviewed. In multivariate analyses, CPS was an independent predictor of fatal outcomes. Higher CPS was associated with greater mortality, however, it was not superior to Charlson methodology in predicting 1-year mortality in this patient cohort.
The addition of a comorbidity score improves multivariate models predicting long-term mortality in older trauma patients. There was no advantage to using CPS instead of Charlson score, and each was an independent predictor of fatal outcomes.
本研究旨在确定两种不同合并症评分(合并症-多药治疗评分[CPS]和 Charlson 评分系统)在大量老年创伤患者中的死亡率预测价值。
在一个城市三级创伤中心,纳入了最初被收入重症监护病房的 55 岁及以上的老年创伤患者。本回顾性图表审查在华盛顿州西雅图的 Harborview 医疗中心进行。从 2010 年 1 月 1 日至 2010 年 12 月 31 日筛选出符合条件的老年创伤患者。从华盛顿州卫生部获得了 1 年死亡率数据。协变量包括年龄、低血压、创伤性脑损伤和损伤严重程度评分。
共回顾了 667 例老年创伤患者的记录。多变量分析显示,CPS 是致命结局的独立预测因素。CPS 越高,死亡率越高,但在预测该患者队列的 1 年死亡率方面,其并不优于 Charlson 方法。
在预测老年创伤患者长期死亡率的多变量模型中,添加合并症评分是有益的。使用 CPS 而不是 Charlson 评分并没有优势,并且两者都是致命结局的独立预测因素。