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对加拿大武装部队人员的三种乙肝病毒标志物的随访研究。

A follow-up study of three hepatitis B virus markers in personnel from the Canadian Armed Forces.

作者信息

Manley K, Embil J, Ostbye T, White L A

出版信息

Mil Med. 1989 Oct;154(10):531-5.

PMID:2515482
Abstract

Prevalence rates for three hepatitis B virus (HBV) markers in two groups of personnel within the Canadian Armed forces (1848 incoming recruits and 210 crew members from a destroyer) were determined. Blood specimens for analysis were provided twice. The initial prevalence rates fell at the lower end of the spectrum when compared with those found in United States military personnel, Canadian military health personnel, and certain Canadian civilian populations. Eleven recruits and one destroyer crew member seroconverted for at least one of the markers between the first and the second testing. Their serological profiles are discussed in detail. No transmission of HBV between individuals in the group of recruits studied was established. However, evidence was found for a probable limited transmission of HBV between two crew members of HMCS Margaree. These findings combined with the high cost of the hepatitis B vaccine indicate that mass immunization for HBV in the Canadian Forces population cannot be justified on the basis of this study.

摘要

测定了加拿大武装部队两组人员(1848名新兵和一艘驱逐舰上的210名船员)中三种乙肝病毒(HBV)标志物的流行率。提供了两份用于分析的血样。与美国军事人员、加拿大军事卫生人员以及某些加拿大平民群体中的流行率相比,初始流行率处于较低水平。在第一次和第二次检测之间,11名新兵和1名驱逐舰船员至少有一项标志物发生了血清学转换。详细讨论了他们的血清学特征。在所研究的新兵群体中,未证实HBV在个体之间传播。然而,发现有证据表明,在玛格丽号皇家加拿大海军舰艇的两名船员之间可能存在有限的HBV传播。这些发现与乙肝疫苗的高成本相结合,表明基于这项研究,加拿大部队人群中大规模接种乙肝疫苗是不合理的。

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