Embil J A, Manley K, White L A
Mil Med. 1989 Sep;154(9):461-5.
Sera were collected from 3958 Canadian Forces personnel, including recruits, personnel posted to bases in Canada and on rotation with United Nations Peacekeeping forces, and the crew of a Canadian destroyer. All sera were tested for the presence of anti-hepatitis A antibodies by a competitive radioimmunoassay. The overall prevalence of anti-hepatitis A antibodies was found to be 23.5% (3.2% to 40.0%). The incidence of viral hepatitis A, as measured by seroconversion in paired sera, was found to be 0.17% (0.01% to 1.42%). The study results support the existence of a direct relationship between increasing age and an increased prevalence of anti-hepatitis A antibodies.
研究人员收集了3958名加拿大军队人员的血清样本，这些人员包括新兵、派驻加拿大境内基地以及参与联合国维和部队轮值的人员，还有一艘加拿大驱逐舰上的船员。所有血清样本均采用竞争性放射免疫测定法检测抗甲型肝炎抗体的存在情况。结果发现，抗甲型肝炎抗体的总体流行率为23.5%（3.2%至40.0%）。通过配对血清中的血清转化情况来衡量，甲型病毒性肝炎的发病率为0.17%（0.01%至1.42%）。研究结果支持年龄增长与抗甲型肝炎抗体流行率增加之间存在直接关系这一观点。
