RTI International Waltham, Massachusetts;
Pediatric Practice Research Group, Mary Ann & J. Milburn Smith Child Health Research Program, Stanley Manne Children's Research Institute, Chicago, Illinois; Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois;
Pediatrics. 2014 Sep;134(3):e732-8. doi: 10.1542/peds.2014-0876.
Cardiovascular disease (CVD) and underlying atherosclerosis begin in childhood and are related to CVD risk factors. This study evaluates tools and strategies to enhance adoption of new CVD risk reduction guidelines for children.
Thirty-two practices, recruited and supported by 2 primary care research networks, were cluster randomized to a multifaceted controlled intervention. Practices were compared with guideline-based individual and composite measures for BMI, blood pressure (BP), and tobacco. Composite measures were constructed by summing the numerators and denominators of individual measures. Preintervention and postintervention measures were assessed by medical record review of children ages 3 to 11 years. Changes in measures (pre-post and intervention versus control) were compared.
The intervention group BP composite improved by 29.5%, increasing from 49.7% to 79.2%, compared with the control group (49.5% to 49.6%; P < .001). Intervention group BP interpretation improved by 61.1% (from 0.2% to 61.3%), compared with the control group (0.4% to 0.6%; P < .001). The assessment of tobacco exposure or use for 5- to 11-year-olds in the intervention group improved by 30.3% (from 3.4% to 49.1%) versus the control group (0.6% to 21.4%) (P = .042). No significant change was seen in the BMI or tobacco composites measures. The overall composite of 9 measures improved by 13.4% (from 48.2% to 69.8%) for the intervention group versus the control group (47.4% to 55.2%) (P = .01).
Significant improvement was demonstrated in the overall composite measure, the composite measure of BP, and tobacco assessment and advice for children aged 5 to 11 years.
心血管疾病(CVD)和潜在的动脉粥样硬化始于儿童时期,并与 CVD 风险因素有关。本研究评估了增强儿童采用新 CVD 风险降低指南的工具和策略。
32 家诊所通过 2 个初级保健研究网络招募并得到支持,被分为多方面对照干预组。诊所与基于指南的 BMI、血压(BP)和烟草的个体和综合措施进行比较。综合措施通过将个体措施的分子和分母相加来构建。通过对 3 至 11 岁儿童的病历回顾来评估干预前和干预后的措施。比较措施的变化(干预前后和干预组与对照组)。
与对照组(49.5%到 49.6%;P <.001)相比,干预组的 BP 综合改善了 29.5%,从 49.7%增加到 79.2%。与对照组(0.4%到 0.6%;P <.001)相比,干预组的 BP 解释率提高了 61.1%。与对照组(0.6%到 21.4%)相比,干预组 5 至 11 岁儿童烟草暴露或使用的评估提高了 30.3%(从 3.4%到 49.1%)(P =.042)。BMI 或烟草综合措施未见明显变化。与对照组(47.4%到 55.2%)相比,干预组的 9 项综合措施的整体综合改善了 13.4%(从 48.2%到 69.8%)(P =.01)。
5 至 11 岁儿童的总体综合措施、BP 综合措施以及烟草评估和建议均有显著改善。