富含血小板血浆在软骨形成中的应用。
Platelet-rich plasma application in chondrogenesis.
作者信息
Kabiri Azadeh, Esfandiari Ebrahim, Esmaeili Abolghasem, Hashemibeni Batool, Pourazar Abbas, Mardani Mohammad
机构信息
Department of Anatomical Sciences, Paramedical School, Guilan University of Medical Sciences, Langeroud, Iran.
Department of Anatomical Sciences and Molecular Biology, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
Adv Biomed Res. 2014 Jun 25;3:138. doi: 10.4103/2277-9175.135156. eCollection 2014.
Abstract
Platelet-rich plasma (PRP), an autologous derivative of whole blood, has been recently used in surgical treatment. PRP contains growth factors including transforming growth factor-β (TGF-β), insulin-like growth factor (IGF), platelet-derived growth factor (PDGF), basic fibroblast growth factor (bFGF), and vascular endothelial growth factor (VEGF) and also bioactive proteins that influence the healing of tendon, ligament, muscle, and bone. This article describes the current clinical applications of PRP in chondrogenesis. This study reviews and evaluates the studies that have been published in the field of chondrogenesis. All aspects of using PRP in chondrogenesis are reviewed.
摘要
富血小板血浆（PRP）是全血的一种自体衍生物，最近已用于外科治疗。PRP含有多种生长因子，包括转化生长因子-β（TGF-β）、胰岛素样生长因子（IGF）、血小板衍生生长因子（PDGF）、碱性成纤维细胞生长因子（bFGF）和血管内皮生长因子（VEGF），还含有影响肌腱、韧带、肌肉和骨骼愈合的生物活性蛋白。本文介绍了PRP在软骨形成中的当前临床应用。本研究回顾并评估了软骨形成领域已发表的研究。对在软骨形成中使用PRP的各个方面进行了综述。
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