与冷漠相比，焦虑和抑郁与帕金森病生活质量的相关性更强。
Anxiety and Depression Are Better Correlates of Parkinson's Disease Quality of Life Than Apathy.
作者信息
Jones Jacob D, Butterfield London C, Song Woojin, Lafo Jacob, Mangal Paul, Okun Michael S, Bowers Dawn
机构信息
From the Dept. of Clinical and Health Psychology (JDJ, LCB, JL, PM, DB), Dept. of Neurology (MSO, DB), and Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL; and Dept. of Psychiatry, University of Michigan, Ann Arbor, MI (WS).
出版信息
J Neuropsychiatry Clin Neurosci. 2015 Summer;27(3):213-8. doi: 10.1176/appi.neuropsych.13120380. Epub 2014 Oct 31.
Due to controversy regarding the influence of apathy on quality of life (QoL), the authors examined the independent influence of apathy, depression, and trait anxiety in a nondemented sample of patients with Parkinson disease (PD). Participants (N=107) completed standard self-report measures of QoL and mood/motivation. Analyses investigated the contribution of these measures and empirically derived factor scores on QoL. QoL was predicted by trait anxiety, dysphoria, and decreased interest, with no independent contribution of apathy. Different patterns emerged with respect to domain-specific QoL, with trait anxiety being the strongest predictor across most domains. Anxiety was most widely related to QoL in PD, with minimal contribution of apathy. Future studies should examine different roles of PD mood/motivation symptoms on caregiver QoL.
由于冷漠对生活质量（QoL）的影响存在争议，作者在非痴呆帕金森病（PD）患者样本中研究了冷漠、抑郁和特质焦虑的独立影响。参与者（N = 107）完成了生活质量和情绪/动机的标准自我报告测量。分析研究了这些测量指标以及根据经验得出的因子得分对生活质量的贡献。特质焦虑、烦躁不安和兴趣降低可预测生活质量，冷漠无独立贡献。在特定领域的生活质量方面出现了不同模式，特质焦虑是大多数领域中最强的预测因子。焦虑与帕金森病患者的生活质量关系最为广泛，冷漠的贡献最小。未来的研究应探讨帕金森病情绪/动机症状对照顾者生活质量的不同作用。
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