Assanelli Deodato, Levaggi Rosella, Carré François, Sharma Sanjay, Deligiannis Asterios, Mellwig Klaus Peter, Tahmi Mohamed, Vinetti Giovanni, Aliverti Paola
Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy,
Intern Emerg Med. 2015 Mar;10(2):143-50. doi: 10.1007/s11739-014-1123-2. Epub 2014 Aug 28.
The aim of this study is to evaluate the cost-effectiveness of ECG in combination with family and personal history and physical examination in order to detect cardiovascular diseases that might cause sudden death in athletes. The study was conducted on a cohort of 6,634, mainly young professional and recreational athletes, 1,071 from Algeria and 5,563 from Europe (France, Germany and Greece). Each athlete underwent medical history, physical examination, and resting 12-lead ECG. 293 athletes (4.4 %), 149 in Europe (2.7 %) and 144 in Algeria (13.4 %) required further tests, and 56 were diagnosed with cardiovascular disease and thus disqualified. The cost-effectiveness ratio (CER) was calculated as the ratio between the cost of screening and the number of statistical life-years saved by the intervention. The estimated reduced risk of death deriving from treatment or disqualification resulted in the saving of 79.1 statistical life-years in Europe and 136.3 in Algeria. CER of screening was 4,071 purchasing-power-parity-adjusted US dollars ($PPP) in Europe and 582 $PPP in Algeria. The results of this study strongly support the utilisation of 12-lead ECG in the pre-participation screening of young athletes, especially in countries where secondary preventive care is not highly developed.
本研究的目的是评估心电图结合家族史、个人史及体格检查在检测可能导致运动员猝死的心血管疾病方面的成本效益。该研究针对6634名运动员开展,主要是年轻的职业和业余运动员,其中1071名来自阿尔及利亚,5563名来自欧洲(法国、德国和希腊)。每位运动员都接受了病史询问、体格检查及静息12导联心电图检查。293名运动员(4.4%)需要进一步检查,其中欧洲有149名(2.7%),阿尔及利亚有144名(13.4%),56名被诊断患有心血管疾病并因此被取消参赛资格。成本效益比(CER)计算为筛查成本与干预措施挽救的统计生命年数之比。经估计,因治疗或取消资格而降低的死亡风险在欧洲挽救了79.1个统计生命年,在阿尔及利亚挽救了136.3个统计生命年。欧洲筛查的CER为4071购买力平价调整后的美元($PPP),阿尔及利亚为582 $PPP。本研究结果有力支持在年轻运动员参赛前筛查中使用12导联心电图,尤其是在二级预防保健不太发达的国家。