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Small-Molecule End-Groups of Linear Polymer Determine Cell-type Gene-Delivery Efficacy.
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Effects of base polymer hydrophobicity and end-group modification on polymeric gene delivery.
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Recent advances in nonviral vectors for gene delivery.
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Parallel synthesis and screening of polymers for nonviral gene delivery.
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Differentially Branched Ester Amine Quadpolymers with Amphiphilic and pH-Sensitive Properties for Efficient Plasmid DNA Delivery.
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Branching in poly(amine-co-ester) polyplexes impacts mRNA transfection.
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Poly(β-amino ester)s-Based Delivery Systems for Targeted Transdermal Vaccination.
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A Polymeric Nanoparticle Formulation for Targeted mRNA Delivery to Fibroblasts.
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Machine learning guided structure function predictions enable in silico nanoparticle screening for polymeric gene delivery.
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Photocrosslinked Bioreducible Polymeric Nanoparticles for Enhanced Systemic siRNA Delivery as Cancer Therapy.
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High-throughput screening of nanoparticles in drug delivery.
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Rapid Optimization of Gene Delivery by Parallel End-modification of Poly(β-amino ester)s.
Mol Ther. 2007 Jul;15(7):1306-1312. doi: 10.1038/sj.mt.6300132. Epub 2016 Dec 7.
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Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells.
Cancer Biol Ther. 2008 Oct;7(10):1584-90. doi: 10.4161/cbt.7.10.6562. Epub 2008 Oct 3.
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Nanoparticles for gene transfer to human embryonic stem cell colonies.
Nano Lett. 2008 Oct;8(10):3126-30. doi: 10.1021/nl8012665. Epub 2008 Aug 29.
4
A combinatorial polymer library approach yields insight into nonviral gene delivery.
Acc Chem Res. 2008 Jun;41(6):749-59. doi: 10.1021/ar7002336.
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Electrostatic ligand coatings of nanoparticles enable ligand-specific gene delivery to human primary cells.
Nano Lett. 2007 Apr;7(4):874-9. doi: 10.1021/nl062395b. Epub 2007 Mar 16.
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Biodegradable polymeric vectors for gene delivery to human endothelial cells.
Bioconjug Chem. 2006 Sep-Oct;17(5):1162-9. doi: 10.1021/bc0600968.
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Polymers for gene delivery across length scales.
Nat Mater. 2006 Jun;5(6):439-51. doi: 10.1038/nmat1645.
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Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery.
Pharmacol Rev. 2006 Mar;58(1):32-45. doi: 10.1124/pr.58.1.8.
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Design and development of polymers for gene delivery.
Nat Rev Drug Discov. 2005 Jul;4(7):581-93. doi: 10.1038/nrd1775.
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A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy.
Mol Ther. 2005 Jun;11(6):990-5. doi: 10.1016/j.ymthe.2005.02.010.

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