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[用于对传统治疗耐药的伤寒乙感染的抗生素及其使用结果]

[Antibiotics used for paratyphi B infections resistant to classical treatment and the results of their use].

作者信息

Taşdemir H A, Albayrak D

机构信息

Erzincan Devlet Hastanesi, Cocuk Hastaliklari Uzmani.

出版信息

Mikrobiyol Bul. 1989 Jan;23(1):35-9.

PMID:2516600
Abstract

Salmonella paratyphi B is a pathogenic agent causing outbreaks and keeping epidemiologic importance. The classical treatment of this disease is made by ampicillin, chloramphenicol, and co-trimoxazole in resistant strain. The resistant strains tends to cause a treatment problem. We report treatment and antibiogram results of 48 patients exactly diagnosed as paratyphi B infection by clinic and laboratory evaluation. These patients came to pediatric clinic of Erzincan state Hospital from Erzincan town and its backgrounds and had ages between 3 months and 5 years. All isolates were resistant to ampicillin, chloramphenicol and cotrimoxazole but usually sensitive to 3. generation cephalosporins (Cefotaxime had greatest sensitivity ratio with 79.1%) and amikacin.

摘要

副伤寒乙沙门氏菌是一种引发疫情且在流行病学上具有重要意义的病原体。针对这种疾病的经典治疗方法是使用氨苄西林、氯霉素以及复方新诺明来治疗耐药菌株。耐药菌株往往会引发治疗难题。我们报告了48例经临床和实验室评估确诊为副伤寒乙感染患者的治疗及药敏试验结果。这些患者来自埃尔津詹镇及其周边地区,前往埃尔津詹州立医院儿科就诊,年龄在3个月至5岁之间。所有分离菌株对氨苄西林、氯霉素和复方新诺明均耐药,但通常对第三代头孢菌素(头孢噻肟的敏感性最高,为79.1%)和阿米卡星敏感。

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