Tanaka K, Shimada M, Naruto T, Yamamoto H, Nishizawa K, Saeki Y
Acta Paediatr Jpn. 1989 Apr;31(2):136-43. doi: 10.1111/j.1442-200x.1989.tb01279.x.
Mass fragmentography was used to analyze the very long-chain fatty acid (VLCFA) composition of erythrocyte membrane phospholipids. The VLCFA content decreased in the order sphingomyelin (SM), phosphatidylcholine (PC) and phosphatidylethanolamine (PE). The tetracosanoic acid (C24:0) and hexacosanoic acid (C26:0) content of both SM and PC in patients with adrenoleukodystrophy (ALD) were significantly higher than those in controls. The VLCFA content of PE was too small, in comparison with those of SM, to be accurately determined.
采用质量碎片分析法分析红细胞膜磷脂中极长链脂肪酸（VLCFA）的组成。VLCFA含量按鞘磷脂（SM）、磷脂酰胆碱（PC）和磷脂酰乙醇胺（PE）的顺序降低。肾上腺脑白质营养不良（ALD）患者的SM和PC中的二十四烷酸（C24:0）和二十六烷酸（C26:0）含量均显著高于对照组。与SM相比，PE的VLCFA含量过小，无法准确测定。
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