Shin K, Nagai Y, Ono I, Sumasaki R, Takita H
Acta Paediatr Jpn. 1989 Apr;31(2):177-9. doi: 10.1111/j.1442-200x.1989.tb01286.x.
A retrospective study on fifty-three patients born to hepatitis B surface antigen (HBs antigen) positive mothers was carried out. Among 17 patients born to hepatitis B e antigen (HBe antigen) negative mothers, six patients received hepatitis B(HB) vaccination and eleven did not. None of the six patients who had received HB vaccination showed seroconversion, while six of the 11 patients (54.5%) without HB vaccination did show seroconversion. There was no definite correlation between the frequency of seroconversion and the administration of HB immune globulin (HBIG). HB vaccination alone may be sufficient to protect infants born to HBe antigen negative mothers from HB viral infection.
对53名母亲为乙肝表面抗原（HBs抗原）阳性的婴儿进行了一项回顾性研究。在17名母亲为乙肝e抗原（HBe抗原）阴性的婴儿中，6名婴儿接种了乙肝（HB）疫苗，11名未接种。接种HB疫苗的6名婴儿均未出现血清转化，而未接种HB疫苗的11名婴儿中有6名（54.5%）出现了血清转化。血清转化频率与乙肝免疫球蛋白（HBIG）的使用之间没有明确的相关性。单独接种HB疫苗可能足以保护母亲为HBe抗原阴性的婴儿免受HB病毒感染。
