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对术前存在酒精使用障碍的肩关节置换术患者围手术期发病率和死亡率的分析。

Analysis of perioperative morbidity and mortality in shoulder arthroplasty patients with preexisting alcohol use disorders.

作者信息

Ponce Brent A, Oladeji Lasun O, Raley James A, Menendez Mariano E

机构信息

Division of Orthopaedic Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.

Division of Orthopaedic Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.

出版信息

J Shoulder Elbow Surg. 2015 Feb;24(2):167-73. doi: 10.1016/j.jse.2014.05.019. Epub 2014 Aug 29.

Abstract

BACKGROUND

Shoulder arthroplasty is becoming increasingly popular in the United States. Given the high prevalence of alcohol abuse and its implications in postoperative morbidity and the increasing incidence of shoulder arthroplasty, it is prudent to explore the effect of alcohol use disorders (AUDs) in this patient population. In this study, we considered numerous outcome variables, including perioperative complications, in-hospital death, prolonged hospital stay, and nonroutine discharge.

METHODS

Using the Nationwide Inpatient Sample, we performed a retrospective cohort study to identify a population of 422,371 adults (≥18 years old) undergoing total shoulder arthroplasty or hemiarthroplasty between January 1, 2002, and December 31, 2011. We then further subdivided this cohort into those who were classified as having AUDs and those who did not. Comparisons of early postoperative outcome measures were performed by bivariate and multivariable analyses with logistic regression modeling.

RESULTS

Compared with those without AUDs, patients undergoing shoulder arthroplasty with a preexisting AUD have a greater likelihood to experience death, pneumonia, deep venous thrombosis, acute renal failure, transfusion, prolonged length of stay, and nonroutine discharge irrespective of age, gender, race, and other medical comorbidities. Patients with a preexisting AUD are 2.7 times more likely to experience perioperative complications after shoulder arthroplasty.

CONCLUSION

Patients undergoing shoulder arthroplasty with a preexisting AUD have a greater likelihood of perioperative complications and health care resource utilization after shoulder arthroplasty. Presurgical alcohol screening may prove effective in identifying at-risk patients, and providing interventions before surgery may effectively limit the complication profile.

摘要

背景

肩关节置换术在美国越来越普遍。鉴于酒精滥用的高发生率及其对术后发病率的影响,以及肩关节置换术发病率的不断上升,探讨酒精使用障碍(AUDs)对该患者群体的影响是明智的。在本研究中,我们考虑了众多结局变量,包括围手术期并发症、院内死亡、住院时间延长和非常规出院。

方法

利用全国住院患者样本,我们进行了一项回顾性队列研究,以确定2002年1月1日至2011年12月31日期间接受全肩关节置换术或半肩关节置换术的422371名成年人(≥18岁)。然后,我们将该队列进一步细分为被归类为患有酒精使用障碍的患者和未患酒精使用障碍的患者。通过双变量和多变量分析以及逻辑回归模型对术后早期结局指标进行比较。

结果

与没有酒精使用障碍的患者相比,术前患有酒精使用障碍的肩关节置换术患者无论年龄、性别、种族和其他合并症如何,都更有可能经历死亡、肺炎、深静脉血栓形成、急性肾衰竭、输血、住院时间延长和非常规出院。术前患有酒精使用障碍的患者在肩关节置换术后发生围手术期并发症的可能性高2.7倍。

结论

术前患有酒精使用障碍的肩关节置换术患者在肩关节置换术后发生围手术期并发症和医疗资源利用的可能性更大。术前酒精筛查可能被证明对识别高危患者有效,并且在手术前提供干预措施可能有效地限制并发症情况。

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