Chiu Anthony K, Cuero Kendrick J, Agarwal Amil R, Fuller Samuel I, Kreulen R Timothy, Best Matthew J, Srikumaran Uma
Department of Orthopaedic Surgery, George Washington University Hospital, Washington, DC, USA.
Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Shoulder Elbow. 2024 Jul;16(3):250-257. doi: 10.1177/17585732231165526. Epub 2023 Apr 6.
Alcohol use disorder (AUD) is the most prevalent substance use disorder in the United States. However, the current literature on AUD as a preoperative risk factor for Total Shoulder Arthroplasty (TSA) outcomes is limited. The purpose of this study was to identify the association of AUD with revision rates and 90-day postoperative complications in TSA.
A retrospective study was conducted using the PearlDiver database. Patients diagnosed with AUD were identified. Patients in remission or with underlying cirrhosis were excluded. Outcomes included 2-year revision, 90-day readmission, 90-day emergency, and 90-day post-operative medical complications. Analysis was performed with univariate chi-squared tests followed by multivariable logistic regression.
A total of 59,261 patients who underwent TSA for osteoarthritis were identified, with 1522 patients having a diagnosis of AUD. Multivariable logistic regression showed that patients with AUD were more likely to undergo 2-year all-cause revision (OR = 1.49, = 0.007), 2-year aseptic revision (OR = 1.47, = 0.014), 90-day hospital readmission (OR = 1.57, = 0.015), and 90-day transient mental disorder (OR = 2.13, = 0.026).
AUD is associated with increased rates of 2-year revision surgery, as well as 90-day readmission and 90-day transient mental disorder following primary TSA for osteoarthritis. These findings may assist orthopedic surgeons in counseling patients with AUD during the pre-operative course.
酒精使用障碍(AUD)是美国最普遍的物质使用障碍。然而,目前关于AUD作为全肩关节置换术(TSA)结果的术前危险因素的文献有限。本研究的目的是确定AUD与TSA翻修率和术后90天并发症之间的关联。
使用PearlDiver数据库进行一项回顾性研究。确定被诊断为AUD的患者。排除缓解期或有潜在肝硬化的患者。结果包括2年翻修、90天再入院、90天急诊和90天术后医疗并发症。采用单变量卡方检验,然后进行多变量逻辑回归分析。
共确定了59261例因骨关节炎接受TSA的患者,其中1522例被诊断为AUD。多变量逻辑回归显示,AUD患者更有可能接受2年全因翻修(OR = 1.49,P = 0.007)、2年无菌翻修(OR = 1.47,P = 0.014)、90天住院再入院(OR = 1.57,P = 0.015)和90天短暂性精神障碍(OR = 2.13,P = 0.026)。
AUD与2年翻修手术率增加以及骨关节炎初次TSA术后90天再入院和90天短暂性精神障碍有关。这些发现可能有助于骨科医生在术前过程中为患有AUD的患者提供咨询。