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感染人类免疫缺陷病毒的女性的性腺功能与生殖健康

Gonadal function and reproductive health in women with human immunodeficiency virus infection.

作者信息

Yalamanchi Swaytha, Dobs Adrian, Greenblatt Ruth M

机构信息

Department of Endocrinology, Diabetes and Metabolism, Johns Hopkins University School of Medicine, 1830 Monument Street, Baltimore, MD 21287, USA.

Department of Clinical Pharmacy, University of California, San Francisco Schools of Pharmacy and Medicine, 405 Irving Street, Second Floor, San Francisco, CA 94122, USA; Department of Medicine, University of California, San Francisco Schools of Pharmacy and Medicine, 405 Irving Street, Second Floor, San Francisco, CA 94122, USA; Department of Epidemiology and Biostatistics, University of California, San Francisco Schools of Pharmacy and Medicine, 405 Irving Street, Second Floor, San Francisco, CA 94122, USA.

出版信息

Endocrinol Metab Clin North Am. 2014 Sep;43(3):731-41. doi: 10.1016/j.ecl.2014.05.002.

Abstract

Most human immunodeficiency virus (HIV) infections among women occur early in reproductive life, which highlights the importance of understanding the impact of HIV on reproductive functions, and also the potential implications of reproductive function and aging on the course of HIV disease. Ovarian function is a crucial component of reproductive biology in women, but standard assessment methods are of limited applicability to women with chronic diseases such as HIV. Pregnancy can now be achieved without transmission of HIV to sexual partner or newborn, but complications of pregnancy may be more common in women infected with HIV than uninfected women.

摘要

大多数女性感染人类免疫缺陷病毒(HIV)发生在生殖生命早期,这凸显了了解HIV对生殖功能影响的重要性,以及生殖功能和衰老对HIV疾病进程的潜在影响。卵巢功能是女性生殖生物学的关键组成部分,但标准评估方法对患有诸如HIV等慢性疾病的女性适用性有限。现在可以实现妊娠而不将HIV传播给性伴侣或新生儿,但感染HIV的女性妊娠并发症可能比未感染女性更为常见。

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