2008 - 2012年德克萨斯州献血者中的克氏锥虫筛查
Trypanosoma cruzi screening in Texas blood donors, 2008-2012.
作者信息
Garcia M N, Woc-Colburn L, Rossmann S N, Townsend R L, Stramer S L, Bravo M, Kamel H, Beddard R, Townsend M, Oldham R, Bottazzi M E, Hotez P J, Murray K O
机构信息
Section of Pediatric Tropical Medicine,Department of Pediatrics,National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital,Houston,TX,USA.
Gulf Coast Regional Blood Center,Houston,TX,USA.
出版信息
Epidemiol Infect. 2016 Apr;144(5):1010-3. doi: 10.1017/S0950268814002234. Epub 2014 Aug 29.
Chagas disease is an important emerging disease in Texas that results in cardiomyopathy in about 30% of those infected with the parasite Trypanosoma cruzi. Between the years 2008 and 2012, about 1/6500 blood donors were T. cruzi antibody-confirmed positive. We found older persons and minority populations, particularly Hispanic, at highest risk for screening positive for T. cruzi antibodies during routine blood donation. Zip code analysis determined that T. cruzi is associated with poverty. Chagas disease has a significant disease burden and is a cause of substantial economic losses in Texas.
恰加斯病是德克萨斯州一种重要的新出现疾病，约30%感染克氏锥虫寄生虫的人会因此患上心肌病。在2008年至2012年期间，约1/6500的献血者经克氏锥虫抗体检测呈阳性。我们发现，老年人和少数族裔人群，尤其是西班牙裔，在常规献血过程中克氏锥虫抗体筛查呈阳性的风险最高。邮政编码分析确定，克氏锥虫与贫困有关。恰加斯病疾病负担沉重，是德克萨斯州经济重大损失的一个原因。
Zotero 插件