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半月板同种异体移植翻修术的临床结果:至少2年随访

Clinical outcome of revision meniscal allograft transplantation: minimum 2-year follow-up.

作者信息

Yanke Adam B, Chalmers Peter N, Frank Rachel M, Friel Nicole A, Karas Vasili, Cole Brian J

机构信息

Department of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois, U.S.A..

Department of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois, U.S.A.

出版信息

Arthroscopy. 2014 Dec;30(12):1602-8. doi: 10.1016/j.arthro.2014.06.027. Epub 2014 Aug 29.

Abstract

PURPOSE

The purpose of this study was to assess the clinical and radiographic outcomes after revision meniscal allograft transplantation (RMAT).

METHODS

Eleven patients underwent RMAT performed by the senior author (B.J.C.). These patients were studied prospectively and completed standardized outcome surveys (including International Knee Documentation Committee [IKDC], Cincinnati Knee-Rating System, Tegner score, Lysholm score, Short Form-12, Knee Injury and Osteoarthritis Outcome Score [KOOS], and overall satisfaction) preoperatively and annually thereafter for a minimum of 2 years. Radiographic analysis before surgery and at the most recent follow-up included anteroposterior, Rosenberg, lateral, and sunrise views graded by the Kellgren and Lawrence (K & L) scale. The status of the articular cartilage was graded intraoperatively using the Outerbridge classification. Two patients were lost to follow-up and one declined further participation.

RESULTS

The average time to RMAT from the index procedure was 3.45 ± 2.52 years, with a mean follow-up after RMAT of 3.83 ± 1.3 years. One patient progressed to arthroplasty during follow-up and was not included in subjective outcome score follow-up. Clinical outcome scores that demonstrated significant improvements included IKDC (43 ± 12 to 61 ± 16; P = .03) and KOOS pain score (66 ± 12 to 79 ± 11; P = .047). Along with this, the subjective symptom rate significantly improved from 5.0 ± 0.9 preoperatively to 6.7 ± 1.8 postoperatively (P = .011). Radiographic (P = .7) and Outerbridge (P = .809) grading did not show progression. Seven of 8 patients would have surgery again, and satisfaction at final follow-up was 7.6 ± 2.6.

CONCLUSIONS

In this small series with short-term follow-up, RMAT resulted in high patient satisfaction and significant symptom reduction on validated outcome scores (IKDC and KOOS pain score), proving the original hypothesis that outcomes after RMAT would be improved compared with preoperative conditions. Identifiable causes of MAT failure may help predict response to RMAT. Because arthroplasty is still not favored in young active patients, a thorough discussion with the patient is necessary to best align their goals with those of the surgery when considering revision meniscus transplantation.

LEVEL OF EVIDENCE

Level IV, therapeutic case series.

摘要

目的

本研究旨在评估半月板同种异体移植翻修术(RMAT)后的临床和影像学结果。

方法

11例患者接受了由资深作者(B.J.C.)实施的RMAT手术。对这些患者进行前瞻性研究,并在术前及此后每年至少完成2年的标准化结果调查(包括国际膝关节文献委员会[IKDC]、辛辛那提膝关节评分系统、泰格纳评分、莱肖尔姆评分、简明健康状况调查简表12、膝关节损伤和骨关节炎疗效评分[KOOS]以及总体满意度)。术前及最近一次随访时的影像学分析包括前后位、罗森伯格位、侧位和日出位X线片,采用凯尔格伦和劳伦斯(K&L)分级。术中使用奥尔特布里奇分类法对关节软骨状态进行分级。2例患者失访,1例拒绝进一步参与。

结果

从初次手术到RMAT的平均时间为3.45±2.52年,RMAT后的平均随访时间为3.83±1.3年。1例患者在随访期间进展为关节置换术,未纳入主观结果评分随访。显示出显著改善的临床结果评分包括IKDC(43±12至61±16;P=.03)和KOOS疼痛评分(66±12至79±11;P=.047)。与此同时,主观症状率从术前的5.0±0.9显著提高到术后的6.7±1.8(P=.011)。影像学(P=.7)和奥尔特布里奇(P=.809)分级未显示进展。8例患者中有7例愿意再次接受手术,最后一次随访时的满意度为7.6±2.6。

结论

在这个短期随访的小样本系列研究中,RMAT使患者满意度较高,且经验证的结果评分(IKDC和KOOS疼痛评分)显示症状显著减轻,证明了最初的假设,即与术前情况相比,RMAT后的结果会得到改善。可识别的半月板同种异体移植失败原因可能有助于预测对RMAT的反应。由于关节置换术在年轻活跃患者中仍不受青睐,在考虑半月板移植翻修时,有必要与患者进行充分讨论,以使他们的目标与手术目标最佳契合。

证据水平

IV级,治疗性病例系列。

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