Young James, Tudor Francois, Mahmoud Ahmed, Myers Peter
Brisbane Orthopaedic & Sports Medicine Centre, Brisbane Private Hospital, Spring Hill, Brisbane, Queensland, Australia,
Orthop Res Rev. 2017 May 15;9:35-43. doi: 10.2147/ORR.S94378. eCollection 2017.
Meniscal allograft transplantation (MAT) is a possible treatment option for patients with joint pain after meniscectomy. It is necessary that the joint be aligned and stable. Current evidence shows that MAT improves pain and mechanical function in the mid to long term with patients reporting significantly improved outcomes at up to 15 years following surgery. Studies on survivorship showed up to 76% graft survival at 10 years. Recent studies have suggested a chondroprotective effect, but there is, at present, no evidence to support MAT in the prevention of osteoarthritis. This review article reported the current evidence for MAT showing support for fresh frozen, nonirradiated allografts. However, further research is required to determine the ideal indications for MAT, the optimal graft fixation method, and the safest rehabilitation protocol.
半月板同种异体移植（MAT）是半月板切除术后关节疼痛患者的一种可能的治疗选择。关节需要对齐且稳定。目前的证据表明，MAT在中长期可改善疼痛和机械功能，患者报告称术后长达15年时结果有显著改善。关于移植物存活的研究表明，10年时移植物存活率高达76%。最近的研究提出了软骨保护作用，但目前尚无证据支持MAT可预防骨关节炎。这篇综述文章报告了目前支持MAT的证据，表明支持使用新鲜冷冻、未辐照的同种异体移植物。然而，需要进一步研究以确定MAT的理想适应症、最佳移植物固定方法和最安全的康复方案。
