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心脏黏液瘤相关超急性缺血性卒中患者的有效机械取栓治疗

Effective mechanical thrombectomy in a patient with hyperacute ischemic stroke associated with cardiac myxoma.

作者信息

Baek Seol-Hee, Park Soonchan, Lee Nam Joon, Kang Youngjin, Cho Kyung-Hee

机构信息

Department of Neurology, Korea University College of Medicine, Seoul, Republic of Korea.

Department of Radiology, Korea University College of Medicine, Seoul, Republic of Korea; Department of Radiology, School of Medicine, Kyung Hee University, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea.

出版信息

J Stroke Cerebrovasc Dis. 2014 Oct;23(9):e417-9. doi: 10.1016/j.jstrokecerebrovasdis.2014.05.006. Epub 2014 Aug 28.

Abstract

Ischemic stroke is the most common neurologic manifestation of cardiac myxoma. However, there has been no current guideline on the treatment of hyperacute ischemic stroke due to cardiac myxoma. We describe a patient with hyperacute stroke caused by cardiac myxoma who had a good outcome with rapid recanalization through mechanical thrombectomy. A 46-year-old man was admitted with acute symptoms of right side hemiplegia and global aphasia. Brain computed tomography (CT) angiography showed a T occlusion of the left internal carotid artery. Intravenous recombinant tissue plasminogen activator was administered. However, his clinical symptoms did not improve. Thus, we performed endovascular treatment and had a successful outcome. A pathologic examination of the retrieved clot revealed a tumor emboli from a cardiac myxoma. Transthoracic echocardiogram revealed a left atrial myxoma in which a large mass was attached to the posterior wall of the aorta. The patient's neurologic deficits recovered with the exception of left eye blindness. Reperfusion therapy with mechanical thrombectomy might be safe and effective for the rapid revascularization of large vessel occlusions in hyperacute ischemic stroke, from which the tumor thrombi can be retrieved.

摘要

缺血性卒中是心脏黏液瘤最常见的神经学表现。然而,目前尚无关于心脏黏液瘤所致超急性缺血性卒中治疗的指南。我们描述了一例由心脏黏液瘤引起的超急性卒中患者,通过机械取栓实现快速再通,预后良好。一名46岁男性因右侧偏瘫和完全性失语的急性症状入院。脑部计算机断层扫描(CT)血管造影显示左侧颈内动脉T形闭塞。给予静脉注射重组组织型纤溶酶原激活剂。然而,他的临床症状并未改善。因此,我们进行了血管内治疗并取得了成功。对取出的血栓进行病理检查发现来自心脏黏液瘤的肿瘤栓子。经胸超声心动图显示左心房黏液瘤,其中一个大肿块附着于主动脉后壁。除左眼失明外,患者的神经功能缺损得以恢复。对于超急性缺血性卒中的大血管闭塞,采用机械取栓进行再灌注治疗可能是安全有效的,从中可以取出肿瘤血栓。

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