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女性性工作者中的艾滋病病毒治疗流程及抗逆转录病毒疗法:对艾滋病病毒预防的启示

The HIV care cascade and antiretroviral therapy in female sex workers: implications for HIV prevention.

作者信息

Mountain Elisa, Pickles Michael, Mishra Sharmistha, Vickerman Peter, Alary Michel, Boily Marie-Claude

机构信息

Department of Infectious Disease Epidemiology, Imperial College London, London, UK.

出版信息

Expert Rev Anti Infect Ther. 2014 Oct;12(10):1203-19. doi: 10.1586/14787210.2014.948422. Epub 2014 Aug 30.

DOI:10.1586/14787210.2014.948422
PMID:25174997
Abstract

To achieve viral suppression and fully benefit from antiretroviral therapy (ART), it is important that individuals with HIV know that they are HIV infected, link to and remain in HIV care, start and remain on ART and adhere to treatment. In HIV epidemics where female sex workers (FSWs) are key drivers of HIV transmission, the extent to which FSWs use ART and engage in the HIV care cascade could have a considerable impact on HIV transmission from FSWs to the wider population. In this article we review the spectrum of FSW engagement in the HIV care cascade, look at the impact of the HIV care cascade and ART use among FSWs on population-level HIV transmission and discuss HIV prevention for FSWs in the context of ART and the HIV care cascade.

摘要

为了实现病毒抑制并充分受益于抗逆转录病毒疗法(ART),感染艾滋病毒的个体了解自己感染了艾滋病毒、与艾滋病毒护理机构建立联系并持续接受护理、开始并持续接受ART治疗以及坚持治疗非常重要。在女性性工作者(FSW)是艾滋病毒传播主要驱动因素的艾滋病毒流行情况中,FSW使用ART并参与艾滋病毒护理流程的程度可能会对艾滋病毒从FSW传播到更广泛人群产生重大影响。在本文中,我们回顾了FSW参与艾滋病毒护理流程的范围,探讨FSW中艾滋病毒护理流程和ART使用对人群层面艾滋病毒传播的影响,并在ART及艾滋病毒护理流程的背景下讨论针对FSW的艾滋病毒预防措施。

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