Barboni E, Lutaya G
Dip. Biopatologia Umana, Fac. Medicina e Chirurgia, Universitå La Sapienza, Roma.
Biochem Int. 1989 Nov;19(5):1151-8.
It has been known for same time that sulphate ions stimulate liver glycogen phosphorylase b, both in the presence and in the absence of AMP. In the present paper we describe some observations (like a modified method of purification of the enzyme after sulphate treatment of the animals) suggesting that actual changes of the physical properties of the enzyme occur after intravenous injection of sodium sulphate. In order to avoid formation of phosphorylase a these studies were performed on enzyme from phosphorylase-b-kinase deficient (gsd/gsd) rats.
人们早就知道，无论有无AMP存在，硫酸根离子都能刺激肝糖原磷酸化酶b。在本文中，我们描述了一些观察结果（比如在对动物进行硫酸盐处理后对该酶进行纯化的改良方法），这些结果表明在静脉注射硫酸钠后，该酶的物理性质会发生实际变化。为了避免磷酸化酶a的形成，这些研究是在来自磷酸化酶b激酶缺陷（gsd/gsd）大鼠的酶上进行的。
