人脑腺苷受体PET成像
Adenosine receptor PET imaging in human brain.
作者信息
Mishina Masahiro, Ishiwata Kiich
机构信息
Department of Neurological Science, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan; Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
出版信息
Int Rev Neurobiol. 2014;119:51-69. doi: 10.1016/B978-0-12-801022-8.00002-7.
Positron emission tomography (PET) is a nuclear medicine imaging technique that allows in vivo imaging of regional receptor-binding capacity. Advances in radiotracer chemistry have led to the development of novel imaging probes for adenosine receptors, especially adenosine A1 and A2A receptors. In this chapter, we discuss brain PET imaging for adenosine receptors and comparison of radioligands for PET imaging in health and diseases.
正电子发射断层扫描（PET）是一种核医学成像技术，可对区域受体结合能力进行体内成像。放射性示踪剂化学的进展已促成了用于腺苷受体，尤其是腺苷A1和A2A受体的新型成像探针的开发。在本章中，我们将讨论用于腺苷受体的脑PET成像以及PET成像在健康和疾病状态下放射性配体的比较。
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