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一名持续使用唑来膦酸的患者发生自发性髋臼假体周围骨折。

Spontaneous acetabular periprosthetic fracture in a patient continuously having zoledronic acid.

作者信息

Tantavisut Saran, Tanavalee Aree, Thanakit Voranuch, Ngarmukos Srihatach, Wilairatana Vajara, Wangroongsub Yongsak

机构信息

Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

出版信息

Clin Orthop Surg. 2014 Sep;6(3):358-60. doi: 10.4055/cios.2014.6.3.358. Epub 2014 Aug 5.

DOI:10.4055/cios.2014.6.3.358
PMID:25177464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4143526/
Abstract

Zoledronic acid has been used for prevention of osteolytic and osteoblastic bone metastasis. This case report illustrates an undesirable consequence from prolonged usage of zoledronic acid in bone metastasis prevention. Periprosthetic acetabular fracture in a patient treated with zoledronic acid for 7 years was reported. The clinical presentation, radiographic and pathological results were described. This is a rare complication after total hip arthroplasty which should not be ignored especially in patients who received long term bisphosphonate.

摘要

唑来膦酸已被用于预防溶骨性和成骨性骨转移。本病例报告阐述了长期使用唑来膦酸预防骨转移产生的不良后果。报告了一名接受唑来膦酸治疗7年的患者发生髋臼假体周围骨折的情况。描述了其临床表现、影像学和病理结果。这是全髋关节置换术后一种罕见的并发症，尤其在接受长期双膦酸盐治疗的患者中不应被忽视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a1/4143526/2d9867b86620/cios-6-358-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a1/4143526/a776eb71e85b/cios-6-358-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a1/4143526/c105ad0ce3f0/cios-6-358-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a1/4143526/3b35efecc5d8/cios-6-358-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a1/4143526/2d9867b86620/cios-6-358-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a1/4143526/a776eb71e85b/cios-6-358-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a1/4143526/c105ad0ce3f0/cios-6-358-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a1/4143526/3b35efecc5d8/cios-6-358-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a1/4143526/2d9867b86620/cios-6-358-g004.jpg

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2
Traumatic periprosthetic acetabular fracture treated by acute one-stage revision arthroplasty. A case report and review of the literature.急性一期翻修关节成形术治疗创伤性人工髋臼周围骨折。病例报告及文献复习。
Injury. 2010 Apr;41(4):421-4. doi: 10.1016/j.injury.2009.10.005. Epub 2009 Nov 5.
3
Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control study.
Clin Orthop Surg. 2018 Sep;10(3):389-392. doi: 10.4055/cios.2018.10.3.389. Epub 2018 Aug 22.
4
Atypical periprosthetic acetabular fracture in long-term alendronate therapy.长期使用阿仑膦酸盐治疗期间发生的非典型人工髋关节臼骨折
Clin Cases Miner Bone Metab. 2016 Sep-Dec;13(3):209-213. doi: 10.11138/ccmbm/2016.13.3.209. Epub 2017 Feb 10.
5
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Am J Case Rep. 2016 Dec 22;17:973-976. doi: 10.12659/ajcr.900435.
低能量股骨骨折与长期使用双膦酸盐的关联：一项病例对照研究。
Osteoporos Int. 2009 Aug;20(8):1353-62. doi: 10.1007/s00198-008-0805-x. Epub 2008 Dec 9.
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