Meşină Cristian, Vasile Ion, Ciobanu Daniela, Calotă Firmilian, Gruia Corina Lavinia, Streba Liliana, Mogoantă Stelian Ştefăniţă, Pârvănescu Horia, Georgescu Claudia Valentina, Tarniţă Dănuţ Nicolae
Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, Romania;
Rom J Morphol Embryol. 2014;55(2 Suppl):643-7.
Collision tumors of the colon are rare. A 64-year-old man was referred on Emergency County Hospital, Craiova, Romania for the evaluation of intestinal obstruction. Colonoscopy demonstrates the presence of about 9/5 cm sized mass in the rectosigmoid junction. After surgical resection, the rectosigmoid lesion was histopathologically composed of two distinct lesions: mucoid adenocarcinoma in the superficial layer and poorly differentiated neuroendocrin carcinoma in the deeper layer. A rectosigmoid tumor showed two distinct tumors with no admixture or transposition of two neoplastic components. A lymph node metastatic deposit contained both tumors. Immunohistochemical stainings were consistent with mucinous adenocarcinoma and neuroendocrine carcinoma of the two neoplasms. We report this case of colonic collision tumor (mucoid adenocarcinoma and neuroendocrine carcinoma) and review of the literature.
结肠碰撞瘤很罕见。一名64岁男性因肠梗阻被转诊至罗马尼亚克拉约瓦县急诊医院。结肠镜检查显示在直肠乙状结肠交界处有一个大小约为9/5厘米的肿块。手术切除后,直肠乙状结肠病变在组织病理学上由两个不同的病变组成:表层为黏液腺癌,深层为低分化神经内分泌癌。一个直肠乙状结肠肿瘤显示出两个不同的肿瘤,两种肿瘤成分没有混合或移位。一个淋巴结转移灶中包含这两种肿瘤。免疫组织化学染色与这两种肿瘤的黏液腺癌和神经内分泌癌相符。我们报告了这例结肠碰撞瘤(黏液腺癌和神经内分泌癌)病例并对文献进行了综述。