Buyck Inez, Wiersema Jan R
Ghent University, Department of Experimental-Clinical and Health Psychology, Henri Dunantlaan 2, 9000 Gent, Belgium.
Res Dev Disabil. 2014 Dec;35(12):3217-25. doi: 10.1016/j.ridd.2014.08.003. Epub 2014 Aug 30.
This study investigated the stability and state-related characteristics of electroencephalographic (EEG) deviances in attention-deficit/hyperactivity disorder (ADHD). Three minutes resting EEG with eyes closed and eyes open were compared between 21 children with ADHD and 29 typically developing children. Across resting conditions, children with ADHD exhibited divergent topographic distribution for theta, alpha and beta power compared to typically developing children. In addition, less alpha and theta suppression to eye opening was found in children with ADHD, but only in those without comorbid ODD/CD. Findings of the present study refer to a consistent divergence in topographic distribution in ADHD across resting state conditions, yet demonstrate that state-related factors and comorbidity may also contribute to resting EEG deviances in ADHD. The state-related findings are in accord with several theoretical accounts emphasizing the role of contextual and state factors defining deficits in ADHD.
本研究调查了注意缺陷多动障碍（ADHD）中脑电图（EEG）异常的稳定性及与状态相关的特征。比较了21名ADHD儿童和29名发育正常儿童在闭眼和睁眼状态下3分钟的静息脑电图。在静息状态下，与发育正常儿童相比，ADHD儿童的θ波、α波和β波功率呈现出不同的地形分布。此外，仅在无对立违抗障碍/品行障碍（ODD/CD）共病的ADHD儿童中发现，他们对睁眼的α波和θ波抑制较少。本研究结果表明，ADHD在静息状态下的地形分布存在一致的差异，但也表明与状态相关的因素和共病可能也会导致ADHD儿童静息脑电图异常。与状态相关的研究结果与一些理论观点一致，这些观点强调了情境和状态因素在定义ADHD缺陷中的作用。
