Alarcón Ana M, Muñoz Sergio, Kaufman Jay S, Martínez Carlos, Riedemann Pablo, Kaliski Sonia
Department of Public Health- CIGES, Universidad de La Frontera, Manuel Montt 112, Temuco, Chile,
Rheumatol Int. 2015 Apr;35(4):685-9. doi: 10.1007/s00296-014-3123-y. Epub 2014 Sep 2.
The aim of this study was to estimate the contributions of ethnic group and socioeconomic status as social determinants related to disability and disease activity in Chilean Mapuche and non-Mapuche patients with rheumatoid arthritis (RA). Descriptive cross-sectional study with a stratified hospital-based sample of 189 patients in treatment with disease-modifying anti-rheumatic drugs. We assessed disability as categorical variable with the Health Assessment Questionnaire, disease activity with the Disease Activity Score instrument, and socioeconomic status with a standard questionnaire used by the Chilean government. Measures of association, stratified analyses and a multiple logistic regression model were used to analyze the data using the Stata 12.1 software package. Low socioeconomic status (annual income below US$ 7,200) is associated with disability (OR 3.87 CI 1.68-9.20) and Mapuche ethnic identity also contributes to disability (OR 2.48, CI 1.09-5.89). Relevant but not statistically significant in multivariable models were variables such as age, gender and place of residence. RA patients with a low socioeconomic status have almost three times the odds of having a moderate to high disability, independent of their ethnic group, gender or place of residence. Therefore, healthcare efforts should be aimed at promoting early diagnosis and prompt treatment among populations with high levels of poverty, which in the region of the Araucanía means primarily indigenous rural areas.
本研究的目的是评估种族和社会经济地位作为社会决定因素,对智利马普切族和非马普切族类风湿关节炎(RA)患者的残疾和疾病活动的影响。采用描述性横断面研究,以分层抽样的方式从189名接受改善病情抗风湿药物治疗的患者中选取样本,这些患者来自不同医院。我们用健康评估问卷将残疾作为分类变量进行评估,用疾病活动评分工具评估疾病活动,并用智利政府使用的标准问卷评估社会经济地位。使用关联度量、分层分析和多元逻辑回归模型,借助Stata 12.1软件包对数据进行分析。低社会经济地位(年收入低于7200美元)与残疾相关(比值比3.87,置信区间1.68 - 9.20),马普切族身份也与残疾有关(比值比2.48,置信区间1.09 - 5.89)。在多变量模型中,年龄、性别和居住地点等变量虽相关但无统计学意义。社会经济地位低的类风湿关节炎患者出现中度至高度残疾的几率几乎是非马普切族的三倍,且不受其种族、性别或居住地点的影响。因此,医疗保健工作应致力于在贫困程度较高的人群中促进早期诊断和及时治疗,在阿劳卡尼亚地区主要指农村土著地区。