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The metastasis-associated protein S100A4 may be a new potential therapeutic target for rheumatoid arthritis.

作者信息

He Wei, Xu Xiao-Di, Wu Hua

机构信息

Department of Pharmacy, Binhu Hospital of Hefei City, The Third affiliated Hospital of Anhui Medical University, Hefei, 230001, Anhui Province, China.

出版信息

Clin Rheumatol. 2016 Feb;35(2):549-50. doi: 10.1007/s10067-014-2765-1. Epub 2014 Sep 2.

DOI:10.1007/s10067-014-2765-1
PMID:25178779
Abstract
摘要

相似文献

1
The metastasis-associated protein S100A4 may be a new potential therapeutic target for rheumatoid arthritis.转移相关蛋白S100A4可能是类风湿关节炎一个新的潜在治疗靶点。
Clin Rheumatol. 2016 Feb;35(2):549-50. doi: 10.1007/s10067-014-2765-1. Epub 2014 Sep 2.
2
S100A4 is expressed at site of invasion in rheumatoid arthritis synovium and modulates production of matrix metalloproteinases.S100A4在类风湿性关节炎滑膜的侵袭部位表达，并调节基质金属蛋白酶的产生。
Ann Rheum Dis. 2006 Dec;65(12):1645-8. doi: 10.1136/ard.2005.047704.
3
The metastasis associated protein S100A4: a potential novel link to inflammation and consequent aggressive behaviour of rheumatoid arthritis synovial fibroblasts.转移相关蛋白S100A4：类风湿性关节炎滑膜成纤维细胞炎症及后续侵袭性行为之间潜在的新联系。
Ann Rheum Dis. 2008 Nov;67(11):1499-504. doi: 10.1136/ard.2007.079905. Epub 2007 Dec 4.
4
Analyses of differential proteome of human synovial fibroblasts obtained from arthritis.对从关节炎患者获取的人滑膜成纤维细胞的差异蛋白质组分析。
Clin Rheumatol. 2009 Feb;28(2):191-9. doi: 10.1007/s10067-008-1013-y. Epub 2008 Sep 20.
5
Chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by Toll-like receptor 2 ligands.Toll样受体2配体刺激类风湿性关节炎滑膜成纤维细胞的趋化因子分泌
J Immunol. 2004 Jan 15;172(2):1256-65. doi: 10.4049/jimmunol.172.2.1256.
6
From transcriptome to proteome: differentially expressed proteins identified in synovial tissue of patients suffering from rheumatoid arthritis and osteoarthritis by an initial screen with a panel of 791 antibodies.从转录组到蛋白质组：通过使用一组791种抗体进行初步筛选，在类风湿性关节炎和骨关节炎患者的滑膜组织中鉴定出差异表达的蛋白质。
Proteomics. 2003 Jun;3(6):991-1002. doi: 10.1002/pmic.200300412.
7
Up-regulation of metastasis-promoting S100A4 (Mts-1) in rheumatoid arthritis: putative involvement in the pathogenesis of rheumatoid arthritis.类风湿关节炎中促转移蛋白S100A4（Mts-1）的上调：可能参与类风湿关节炎的发病机制。
Arthritis Rheum. 2007 Mar;56(3):779-89. doi: 10.1002/art.22398.
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Detection of differentially expressed genes in synovial fibroblasts by restriction fragment differential display.通过限制性片段差异显示技术检测滑膜成纤维细胞中差异表达的基因。
Rheumatology (Oxford). 2004 Nov;43(11):1346-52. doi: 10.1093/rheumatology/keh347. Epub 2004 Aug 3.
9
Mechanisms and clinical relevance of TRAIL-triggered responses in the synovial fibroblasts of patients with rheumatoid arthritis.类风湿关节炎患者滑膜成纤维细胞中TRAIL触发反应的机制及临床相关性
Arthritis Rheum. 2011 Apr;63(4):904-13. doi: 10.1002/art.30181.
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Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts.类风湿性关节炎滑膜成纤维细胞中Trex-1缺乏
Arthritis Rheum. 2010 Sep;62(9):2673-9. doi: 10.1002/art.27567.

本文引用的文献

1
The metastasis-associated protein S100A4 promotes the inflammatory response of mononuclear cells via the TLR4 signalling pathway in rheumatoid arthritis.转移相关蛋白 S100A4 通过 TLR4 信号通路促进类风湿关节炎中单核细胞的炎症反应。
Rheumatology (Oxford). 2014 Aug;53(8):1520-6. doi: 10.1093/rheumatology/keu031. Epub 2014 Mar 18.
2
Metastasin S100A4 is increased in proportion to radiographic damage in patients with RA.转移性 S100A4 在 RA 患者中与放射学损害成比例增加。
Rheumatology (Oxford). 2012 May;51(5):932-40. doi: 10.1093/rheumatology/ker362. Epub 2012 Jan 17.
3
The metastasis promoting protein S100A4 is increased in idiopathic inflammatory myopathies.
促转移蛋白 S100A4 在特发性炎症性肌病中增加。
Rheumatology (Oxford). 2011 Oct;50(10):1766-72. doi: 10.1093/rheumatology/ker218. Epub 2011 Jun 28.
4
Potential role for S100A4 in the disruption of the blood-brain barrier in collagen-induced arthritic mice, an animal model of rheumatoid arthritis.S100A4 在胶原诱导性关节炎小鼠（类风湿关节炎动物模型）血脑屏障破坏中的潜在作用。
Neuroscience. 2011 Aug 25;189:286-92. doi: 10.1016/j.neuroscience.2011.05.044. Epub 2011 May 26.
5
Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis.转移性诱导 S100A4 蛋白与类风湿关节炎的疾病活动有关。
Rheumatology (Oxford). 2009 Dec;48(12):1590-4. doi: 10.1093/rheumatology/kep316. Epub 2009 Oct 14.
6
Analyses of differential proteome of human synovial fibroblasts obtained from arthritis.对从关节炎患者获取的人滑膜成纤维细胞的差异蛋白质组分析。
Clin Rheumatol. 2009 Feb;28(2):191-9. doi: 10.1007/s10067-008-1013-y. Epub 2008 Sep 20.
7
Up-regulation of metastasis-promoting S100A4 (Mts-1) in rheumatoid arthritis: putative involvement in the pathogenesis of rheumatoid arthritis.类风湿关节炎中促转移蛋白S100A4（Mts-1）的上调：可能参与类风湿关节炎的发病机制。
Arthritis Rheum. 2007 Mar;56(3):779-89. doi: 10.1002/art.22398.
8
S100A4 is expressed at site of invasion in rheumatoid arthritis synovium and modulates production of matrix metalloproteinases.S100A4在类风湿性关节炎滑膜的侵袭部位表达，并调节基质金属蛋白酶的产生。
Ann Rheum Dis. 2006 Dec;65(12):1645-8. doi: 10.1136/ard.2005.047704.
9
Rheumatoid arthritis.类风湿关节炎
Cell. 1996 May 3;85(3):307-10. doi: 10.1016/s0092-8674(00)81109-5.