一名感染人类免疫缺陷病毒（HIV）的患者因肺白念珠菌脓肿接受治疗，期间伏立康唑、达芦那韦/利托那韦与替诺福韦/恩曲他滨之间的药物相互作用。
Drug interactions between voriconazole, darunavir/ritonavir and tenofovir/emtricitabine in an HIV-infected patient treated for Aspergillus candidus lung abscess.
作者信息
Becker A, Sifaoui F, Gagneux M, Desprez S, Vignoli P, Huguet D, Froidure M, Leduc D, Legout L
机构信息
Infectious Diseases Department, Alpes-Leman Hospital, Contamine-sur Arve, France.
Microbiology Department, Alpes-Leman Hospital, Contamine-sur Arve, France.
出版信息
Int J STD AIDS. 2015 Aug;26(9):672-5. doi: 10.1177/0956462414549035. Epub 2014 Sep 1.
PMID:25179636
Abstract
We report an unusual case of pulmonary aspergillosis in a patient with AIDS and we demonstrated the drug-drug interactions between voriconazole, darunavir/ritonavir and tenofovir/emtricitabine. The combination darunavir-ritonavir-voriconazole should be avoided.
摘要
我们报告了一例艾滋病患者发生的罕见肺曲霉病病例，并展示了伏立康唑、达芦那韦/利托那韦和替诺福韦/恩曲他滨之间的药物相互作用。应避免使用达芦那韦-利托那韦-伏立康唑的联合用药。
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